mitochondrial DNA depletion syndrome 6 (hepatocerebral type)

mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a medical condition that may be associated with various symptoms and signs.

Also known as: Navajo neurohepatopathy, Navajo neuropathy, mitochondrial DNA depletion syndrome 6 (hepatocerebral type), MPV17-related hepatocerebral mitochondrial DNA depletion syndrome, MTDPS6, NN, mitochondrial DNA depletion syndrome 6.

Category: General

Looking into mitochondrial DNA depletion syndrome 6 (hepatocerebral type)? See the lab tests healthcare providers may use to investigate mitochondrial DNA depletion syndrome 6 (hepatocerebral type), and learn what each one measures.
Explore tests for mitochondrial DNA depletion syndrome 6 (hepatocerebral type)
Symptoms

Symptoms associated with mitochondrial DNA depletion syndrome 6 (hepatocerebral type)

The following symptoms have been associated with mitochondrial DNA depletion syndrome 6 (hepatocerebral type) in medical literature. Not everyone experiences the same symptoms.

Abdominal distention

Distention of the abdomen....

Digestive

Ankle weakness

Reduced strength of the muscles that lift or otherwise move the foot at the ankle....

General

Constipation

Infrequent or difficult evacuation of feces....

Digestive

Dark urine

An abnormal dark color of the urine....

Genitourinary, Metabolic

Depression

Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover from these m...

Neurological

Diarrhea

Abnormally increased frequency (usually defined as three or more) loose or watery bowel movements a day....

Digestive

Distal muscle weakness

Reduced strength of the musculature of the distal extremities....

General

Dysphagia

Difficulty in swallowing....

Digestive, Neurological

Episodic vomiting

Paroxysmal, recurrent episodes of vomiting....

Digestive

Failure to thrive

Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm....

Growth

Foot dorsiflexor weakness

Weakness of the muscles responsible for dorsiflexion of the foot, that is, of the movement of the toes towards...

Limbs

Gastroesophageal reflux

A condition in which the stomach contents leak backwards from the stomach into the esophagus through the lower...

Digestive

Hearing impairment

A decreased magnitude of the sensory perception of sound....

Otic

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentra...

Dermatologic, Digestive, Gastrointestinal, Integument

Lower limb muscle weakness

Weakness of the muscles of the legs....

Limbs

Memory impairment

An impairment of memory as manifested by a reduced ability to remember things such as dates and names, and inc...

Neurological

Muscle weakness

Reduced strength of muscles....

General

Myalgia

Pain in muscle....

General

Ophthalmoparesis

Ophthalmoplegia is a paralysis or weakness of one or more of the muscles that control eye movement....

Ophthalmic

Poor suck

An inadequate sucking reflex, resulting in the difficult of newborns to be breast-fed....

Digestive

Progressive muscle weakness

Information about Progressive muscle weakness....

General

Progressive proximal muscle weakness

Lack of strength of the proximal muscles that becomes progressively more severe....

General

Prolonged neonatal jaundice

Neonatal jaundice refers to a yellowing of the skin and other tissues of a newborn infant as a result of incre...

Dermatologic, Digestive, Gastrointestinal, Integument

Respiratory insufficiency due to muscle weakness

Information about Respiratory insufficiency due to muscle weakness....

Respiratory

Seizure

A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...

Neurological

Vomiting

Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic...

Digestive

Weakness of the intrinsic hand muscles

Information about Weakness of the intrinsic hand muscles....

Limbs

Tests

Tests used to investigate mitochondrial DNA depletion syndrome 6 (hepatocerebral type)

Healthcare providers may order these tests when evaluating mitochondrial DNA depletion syndrome 6 (hepatocerebral type). Test selection is a clinical decision made by a qualified professional.

CBC with Differential

Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...

Sample: Blood

Comprehensive Metabolic Panel (CMP)

Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...

Sample: Blood

Urinalysis

Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....

Sample: Urine

Related conditions

Conditions with overlapping symptoms

These conditions share symptoms with mitochondrial DNA depletion syndrome 6 (hepatocerebral type), which is why a clinical evaluation is important.

FAQ

Frequently Asked Questions

What is mitochondrial DNA depletion syndrome 6 (hepatocerebral type)?

mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a health condition described in medical literature. mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a medical condition that may be associated with various symptoms and signs.

What are the symptoms of mitochondrial DNA depletion syndrome 6 (hepatocerebral type)?

mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is associated with 27 symptoms in the medical literature we index, including Abdominal distention, Ankle weakness, Constipation, Dark urine, Depression, Diarrhea. Symptoms vary widely between individuals.

How is mitochondrial DNA depletion syndrome 6 (hepatocerebral type) diagnosed or investigated?

A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with mitochondrial DNA depletion syndrome 6 (hepatocerebral type) include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.

Is SymptomDatabase.com diagnosing me?

No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have mitochondrial DNA depletion syndrome 6 (hepatocerebral type), please discuss your symptoms with a qualified healthcare provider.

Educational content only: The information on Symptom Database.com is for educational purposes and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. Read our full disclaimer.