Gastroesophageal reflux
A condition in which the stomach contents leak backwards from the stomach into the esophagus through the lower esophageal sphincter.
Also called: Acid reflux, Acid reflux disease, GERD, GORD, Gastro-esophageal reflux, Gastro-oesophageal reflux, Gastroesophageal reflux disease, Heartburn.
Conditions associated with gastroesophageal reflux
The following conditions have been associated with gastroesophageal reflux in medical literature. This is informational and not a diagnosis.
1p36 deletion syndrome
1p36 deletion syndrome is a medical condition that may be associated with various symptoms and signs....
22q11.2 deletion syndrome
22q11.2 deletion syndrome is a medical condition that may be associated with various symptoms and signs....
3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form
3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form is a medical condition that may be associ...
Alobar holoprosencephaly
Alobar holoprosencephaly is a medical condition that may be associated with various symptoms and signs....
Alpha-N-acetylgalactosaminidase deficiency
Alpha-N-acetylgalactosaminidase deficiency is a medical condition that may be associated with various symptoms...
Alström syndrome
Alström syndrome is a medical condition that may be associated with various symptoms and signs....
Angelman syndrome
Angelman syndrome is a medical condition that may be associated with various symptoms and signs....
Arboleda-Tham syndrome
Arboleda-Tham syndrome is a medical condition that may be associated with various symptoms and signs....
Aromatic L-amino acid decarboxylase deficiency
Aromatic L-amino acid decarboxylase deficiency is a medical condition that may be associated with various symp...
Autosomal dominant progressive external ophthalmoplegia
Autosomal dominant progressive external ophthalmoplegia is a medical condition that may be associated with var...
Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form
Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form is a medical condition tha...
Bilateral generalized polymicrogyria
Bilateral generalized polymicrogyria is a medical condition that may be associated with various symptoms and s...
Bilateral perisylvian polymicrogyria
Bilateral perisylvian polymicrogyria is a medical condition that may be associated with various symptoms and s...
CDKL5-deficiency disorder
CDKL5-deficiency disorder is a medical condition that may be associated with various symptoms and signs....
CLCN4-related X-linked intellectual disability syndrome
CLCN4-related X-linked intellectual disability syndrome is a medical condition that may be associated with var...
CODAS syndrome
Codas syndrome is a multiple congenital anomalies syndrome characterized by Cerebral, Ocular, Dental, Auricula...
CTCF-related neurodevelopmental disorder
A rare, genetic, neurodevelopmental disorder characterized by global developmental delay, borderline to severe...
Carey-Fineman-Ziter syndrome 1
A rare condition characterized by the association of hypotonia, Moebius sequence (bilateral congenital facial ...
Christianson syndrome
Christianson syndrome is a medical condition that may be associated with various symptoms and signs....
Chronic graft versus host disease
Chronic graft versus host disease is a medical condition that may be associated with various symptoms and sign...
Classical Ehlers-Danlos syndrome
Classical Ehlers-Danlos syndrome is a medical condition that may be associated with various symptoms and signs...
Cockayne syndrome
Cockayne syndrome is a medical condition that may be associated with various symptoms and signs....
Cockayne syndrome type 3
Cockayne syndrome type 3 is a medical condition that may be associated with various symptoms and signs....
Coffin-Siris syndrome 12
Coffin-Siris syndrome 12 is a medical condition that may be associated with various symptoms and signs....
Coffin-Siris syndrome 6
Any Coffin-Siris syndrome in which the cause of the disease is a mutation in the ARID2 gene....
Congenital myasthenic syndrome
Congenital myasthenic syndrome is a medical condition that may be associated with various symptoms and signs....
Congenital sucrase-isomaltase deficiency
Congenital sucrase-isomaltase deficiency is a medical condition that may be associated with various symptoms a...
Congenital tracheomalacia
Congenital tracheomalacia is a medical condition that may be associated with various symptoms and signs....
Cornelia de Lange syndrome 1
Any Cornelia de Lange syndrome in which the cause of the disease is a mutation in the NIPBL gene....
Cornelia de Lange syndrome 7
Cornelia de Lange syndrome 7 is a medical condition that may be associated with various symptoms and signs....
Craniofaciofrontodigital syndrome
Craniofaciofrontodigital syndrome is a medical condition that may be associated with various symptoms and sign...
D-glyceric aciduria
A metabolic disorder characterized by D-glyceric acid excretion. It has been described in several patients. Cl...
DEGCAGS syndrome
DEGCAGS syndrome is a medical condition that may be associated with various symptoms and signs....
DYRK1A-related intellectual disability syndrome
DYRK1A-related intellectual disability syndrome is a medical condition that may be associated with various sym...
DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion is a medical condition that...
Dubowitz syndrome
Dubowitz syndrome is a medical condition that may be associated with various symptoms and signs....
Dursun-Ozgul neurodevelopmental syndrome
Dursun-Ozgul neurodevelopmental syndrome is a medical condition that may be associated with various symptoms a...
Emanuel syndrome
Emanuel syndrome is a medical condition that may be associated with various symptoms and signs....
Eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis is a medical condition that may be associated with various sympt...
Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation
Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation is a medica...
Tests providers may use to investigate gastroesophageal reflux
When investigating gastroesophageal reflux, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Liver Function Test
Measures ALT, AST, ALP, bilirubin, and albumin to assess liver health....
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Folate
Measures folate levels to help evaluate anemia and pregnancy health....
Free T4
Measures the active form of thyroxine to help evaluate thyroid function....
Thyroid Stimulating Hormone (TSH)
Screens for thyroid disorders such as hypothyroidism and hyperthyroidism....
Vitamin B12
Detects B12 deficiency which can cause anemia and neurological symptoms....
Symptoms commonly seen alongside gastroesophageal reflux
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if gastroesophageal reflux is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom gastroesophageal reflux mean?
Gastroesophageal reflux is a health sign or symptom described in medical literature. A condition in which the stomach contents leak backwards from the stomach into the esophagus through the lower esophageal sphincter.
Which conditions are associated with gastroesophageal reflux?
Gastroesophageal reflux has been reported in association with 156 conditions in the medical literature we index, including 1p36 deletion syndrome, 22q11.2 deletion syndrome, 3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form, Alobar holoprosencephaly, Alpha-N-acetylgalactosaminidase deficiency. These associations do not mean you have any of these conditions.
Should I see a doctor about gastroesophageal reflux?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.