Distal muscle weakness
Reduced strength of the musculature of the distal extremities.
Also called: Distal limb muscle weakness, Distal limb weakness, Distal muscular weakness, Distal paresis, Muscle weakness, distal, Muscle weakness, distal limbs, due to neuronopathy, Weakness of distal muscles, Weakness of outermost muscles, Distal limb muscle weakness due to peripheral neuropathy.
Conditions associated with distal muscle weakness
The following conditions have been associated with distal muscle weakness in medical literature. This is informational and not a diagnosis.
Acute intermittent porphyria
Acute intermittent porphyria is a medical condition that may be associated with various symptoms and signs....
Adult-onset distal myopathy due to VCP mutation
Adult-onset distal myopathy due to VCP mutation is a medical condition that may be associated with various sym...
Angiostrongyliasis
Angiostrongyliasis is a medical condition that may be associated with various symptoms and signs....
Arachnoid cyst
Arachnoid cyst is a medical condition that may be associated with various symptoms and signs....
Autosomal dominant Charcot-Marie-Tooth disease type 2Y
Autosomal dominant Charcot-Marie-Tooth disease type 2Y is a medical condition that may be associated with vari...
Autosomal dominant Charcot-Marie-Tooth disease type 2Z
Autosomal dominant Charcot-Marie-Tooth disease type 2Z is a medical condition that may be associated with vari...
Bethlem muscular dystrophy
Bethlem muscular dystrophy is a medical condition that may be associated with various symptoms and signs....
Bethlem myopathy 1A
Bethlem myopathy 1A is a medical condition that may be associated with various symptoms and signs....
Carey-Fineman-Ziter syndrome 1
A rare condition characterized by the association of hypotonia, Moebius sequence (bilateral congenital facial ...
Centronuclear myopathy 1
Centronuclear myopathy 1 is a medical condition that may be associated with various symptoms and signs....
Charcot-Marie-Tooth disease X-linked dominant 1
Charcot-Marie-Tooth neuropathy that is inherited in an X-linked manner, and is associated with mutation(s) in ...
Charcot-Marie-Tooth disease type 1E
A rare subtype of CMT1 characterized by a variable clinical presentation. Onset within the first two years of ...
Charcot-Marie-Tooth disease type 1F
Charcot-Marie-Tooth disease type 1F is a medical condition that may be associated with various symptoms and si...
Charcot-Marie-Tooth disease type 4A
Charcot-Marie-Tooth disease type 4A is a medical condition that may be associated with various symptoms and si...
Charcot-Marie-Tooth disease type 4C
Charcot-Marie-Tooth disease type 4C is a medical condition that may be associated with various symptoms and si...
Charcot-Marie-Tooth disease, axonal, Type 2HH
Charcot-Marie-Tooth disease, axonal, Type 2HH is a medical condition that may be associated with various sympt...
Charcot-Marie-Tooth disease, axonal, type 2KK
Charcot-Marie-Tooth disease, axonal, type 2KK is a medical condition that may be associated with various sympt...
Choreoacanthocytosis
Choreoacanthocytosis is a medical condition that may be associated with various symptoms and signs....
Distal myotilinopathy
Distal myotilinopathy is a medical condition that may be associated with various symptoms and signs....
Frontotemporal dementia with motor neuron disease
Frontotemporal dementia with motor neuron disease is a medical condition that may be associated with various s...
Hereditary coproporphyria
Hereditary coproporphyria is a medical condition that may be associated with various symptoms and signs....
Hereditary myopathy with early respiratory failure
Hereditary myopathy with early respiratory failure is a medical condition that may be associated with various ...
Laing distal myopathy
Laing distal myopathy is a medical condition that may be associated with various symptoms and signs....
Lead poisoning
Lead poisoning is a medical condition that may be associated with various symptoms and signs....
Leigh syndrome
Leigh syndrome is a medical condition that may be associated with various symptoms and signs....
Mitochondrial DNA depletion syndrome, myopathic form
Mitochondrial DNA depletion syndrome, myopathic form is a medical condition that may be associated with variou...
Mitochondrial neurogastrointestinal encephalomyopathy
Mitochondrial neurogastrointestinal encephalomyopathy is a medical condition that may be associated with vario...
Myopathy, distal, 1
Myopathy, distal, 1 is a medical condition that may be associated with various symptoms and signs....
Proximal spinal muscular atrophy
Proximal spinal muscular atrophy is a medical condition that may be associated with various symptoms and signs...
Pure mitochondrial myopathy
Pure mitochondrial myopathy is a medical condition that may be associated with various symptoms and signs....
Sandhoff disease, juvenile form
Sandhoff disease, juvenile form is a medical condition that may be associated with various symptoms and signs....
Scleromyxedema
Scleromyxedema is a medical condition that may be associated with various symptoms and signs....
Steinert myotonic dystrophy
Steinert myotonic dystrophy is a medical condition that may be associated with various symptoms and signs....
Synaptic congenital myasthenic syndrome
Synaptic congenital myasthenic syndrome is a medical condition that may be associated with various symptoms an...
Tay-Sachs disease
Tay-Sachs disease is a medical condition that may be associated with various symptoms and signs....
Vocal cord and pharyngeal distal myopathy
Vocal cord and pharyngeal distal myopathy is a medical condition that may be associated with various symptoms ...
amyotrophic lateral sclerosis type 21
Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the MATR3 gene....
congenital muscular dystrophy due to LMNA mutation
Congenital muscular dystrophy due to LMNA mutation is a rare congenital muscular dystrophy characterized by pr...
immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy
immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy is a medical condition th...
mitochondrial DNA depletion syndrome 1
mitochondrial DNA depletion syndrome 1 is a medical condition that may be associated with various symptoms and...
Tests providers may use to investigate distal muscle weakness
When investigating distal muscle weakness, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside distal muscle weakness
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if distal muscle weakness is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom distal muscle weakness mean?
Distal muscle weakness is a health sign or symptom described in medical literature. Reduced strength of the musculature of the distal extremities.
Which conditions are associated with distal muscle weakness?
Distal muscle weakness has been reported in association with 52 conditions in the medical literature we index, including Acute intermittent porphyria, Adult-onset distal myopathy due to VCP mutation, Angiostrongyliasis, Arachnoid cyst, Autosomal dominant Charcot-Marie-Tooth disease type 2Y. These associations do not mean you have any of these conditions.
Should I see a doctor about distal muscle weakness?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.