Progressive proximal muscle weakness
Lack of strength of the proximal muscles that becomes progressively more severe.
Also called: Muscle weakness, progressive, proximal.
Conditions associated with progressive proximal muscle weakness
The following conditions have been associated with progressive proximal muscle weakness in medical literature. This is informational and not a diagnosis.
Alpha-B crystallin-related late-onset myopathy
Alpha-B crystallin-related late-onset myopathy is a medical condition that may be associated with various symp...
Autosomal recessive distal nebulin myopathy
Autosomal recessive distal nebulin myopathy is a medical condition that may be associated with various symptom...
Bethlem muscular dystrophy
Bethlem muscular dystrophy is a medical condition that may be associated with various symptoms and signs....
Distal myotilinopathy
Distal myotilinopathy is a medical condition that may be associated with various symptoms and signs....
Glycogen storage disease due to acid maltase deficiency
Glycogen storage disease due to acid maltase deficiency is a medical condition that may be associated with var...
Glycogen storage disease due to muscle glycogen phosphorylase deficiency
Glycogen storage disease due to muscle glycogen phosphorylase deficiency is a medical condition that may be as...
Late-onset distal myopathy, Markesbery-Griggs type
Late-onset distal myopathy, Markesbery-Griggs type is a medical condition that may be associated with various ...
Mitochondrial DNA depletion syndrome, myopathic form
Mitochondrial DNA depletion syndrome, myopathic form is a medical condition that may be associated with variou...
Myopathy and diabetes mellitus
Myopathy and diabetes mellitus is a medical condition that may be associated with various symptoms and signs....
Neutral lipid storage disease with myopathy
Neutral lipid storage disease with myopathy is a medical condition that may be associated with various symptom...
Oculopharyngodistal myopathy
Oculopharyngodistal myopathy is a medical condition that may be associated with various symptoms and signs....
Plectin-related limb-girdle muscular dystrophy R17
Plectin-related limb-girdle muscular dystrophy R17 is a medical condition that may be associated with various ...
inclusion body myopathy with Paget disease of bone and frontotemporal dementia type 1
A rare autosomal dominant inherited disorder caused by mutations in the VCP gene. It can affect the muscles, b...
mitochondrial DNA depletion syndrome 6 (hepatocerebral type)
mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a medical condition that may be associated wit...
Tests providers may use to investigate progressive proximal muscle weakness
When investigating progressive proximal muscle weakness, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Fasting Glucose
Measures blood sugar after fasting to screen for diabetes and prediabetes....
Hemoglobin A1c (HbA1c)
Reflects average blood sugar over the past 2-3 months....
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside progressive proximal muscle weakness
Constipation
Infrequent or difficult evacuation of feces....
Depression
Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover from these m...
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if progressive proximal muscle weakness is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom progressive proximal muscle weakness mean?
Progressive proximal muscle weakness is a health sign or symptom described in medical literature. Lack of strength of the proximal muscles that becomes progressively more severe.
Which conditions are associated with progressive proximal muscle weakness?
Progressive proximal muscle weakness has been reported in association with 14 conditions in the medical literature we index, including Alpha-B crystallin-related late-onset myopathy, Autosomal recessive distal nebulin myopathy, Bethlem muscular dystrophy, Distal myotilinopathy, Glycogen storage disease due to acid maltase deficiency. These associations do not mean you have any of these conditions.
Should I see a doctor about progressive proximal muscle weakness?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.