Netherton syndrome

Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.

Also known as: Comèl-Netherton syndrome, Ichthyosis, Netherton Syndrome, NS, Netherton syndrome, bamboo hair syndrome, neth.

Category: General

Looking into Netherton syndrome? See the lab tests healthcare providers may use to investigate Netherton syndrome, and learn what each one measures.
Explore tests for Netherton syndrome
Symptoms

Symptoms associated with Netherton syndrome

The following symptoms have been associated with Netherton syndrome in medical literature. Not everyone experiences the same symptoms.

Allergic rhinitis

It is characterized by one or more symptoms including sneezing, itching, nasal congestion, and rhinorrhea....

Head and Neck, Immunologic

Alopecia

A noncongenital process of hair loss, which may progress to partial or complete baldness....

Integument

Chronic constipation

Constipation for longer than three months with fewer than 3 bowel movements per week, straining, lumpy or hard...

Digestive

Chronic diarrhea

The presence of chronic diarrhea, which is usually taken to mean diarrhea that has persisted for over 4 weeks....

Digestive

Diarrhea

Abnormally increased frequency (usually defined as three or more) loose or watery bowel movements a day....

Digestive

Dry skin

Skin characterized by the lack of natural or normal moisture....

Dermatologic, Integument

Dyspnea

Difficult or labored breathing. Dyspnea is a subjective feeling only the patient can rate, e.g., on a Borg sca...

Respiratory

Facial edema

Information about Facial edema....

Head and Neck, Metabolic

Failure to thrive

Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm....

Growth

Hearing impairment

A decreased magnitude of the sensory perception of sound....

Otic

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentra...

Dermatologic, Digestive, Gastrointestinal, Integument

Pruritus

Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally incr...

Dermatologic, Integument

Recurrent fever

Periodic (episodic or recurrent) bouts of fever....

Metabolic

Seizure

A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...

Neurological

Sensorineural hearing impairment

A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlear nerve....

Otic

Skin rash

A red eruption of the skin....

Dermatologic, Immunologic, Integument

Urticaria

Raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis. Urticaria is intens...

Cardiovascular, Dermatologic, Integument

Tests

Tests used to investigate Netherton syndrome

Healthcare providers may order these tests when evaluating Netherton syndrome. Test selection is a clinical decision made by a qualified professional.

CBC with Differential

Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...

Sample: Blood

Comprehensive Metabolic Panel (CMP)

Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...

Sample: Blood

Urinalysis

Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....

Sample: Urine

Related conditions

Conditions with overlapping symptoms

These conditions share symptoms with Netherton syndrome, which is why a clinical evaluation is important.

FAQ

Frequently Asked Questions

What is Netherton syndrome?

Netherton syndrome is a health condition described in medical literature. Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.

What are the symptoms of Netherton syndrome?

Netherton syndrome is associated with 17 symptoms in the medical literature we index, including Allergic rhinitis, Alopecia, Chronic constipation, Chronic diarrhea, Diarrhea, Dry skin. Symptoms vary widely between individuals.

How is Netherton syndrome diagnosed or investigated?

A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with Netherton syndrome include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.

Is SymptomDatabase.com diagnosing me?

No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have Netherton syndrome, please discuss your symptoms with a qualified healthcare provider.

Educational content only: The information on Symptom Database.com is for educational purposes and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. Read our full disclaimer.