Omenn syndrome
An inflammatory condition characterized by erythroderma, desquamation, alopecia, chronic diarrhea, failure to thrive, lymphadenopathy, and hepatosplenomegaly, associated with severe combined immunodeficiency (SCID).
Also known as: Omenn syndrome, combined immunodeficiency with hypereosinophilia, reticuloendotheliosis familial with eosinophilia.
Category: General
Symptoms associated with Omenn syndrome
The following symptoms have been associated with Omenn syndrome in medical literature. Not everyone experiences the same symptoms.
Alopecia
A noncongenital process of hair loss, which may progress to partial or complete baldness....
Alopecia of scalp
Information about Alopecia of scalp....
Diarrhea
Abnormally increased frequency (usually defined as three or more) loose or watery bowel movements a day....
Edema
An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body....
Failure to thrive
Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm....
Generalized lymphadenopathy
A generalized form of lymphadenopathy....
Intractable diarrhea
Information about Intractable diarrhea....
Persistent fever
Fever that persists longer than expected for an acute infectious disease. No precise threshold exists, and the...
Protracted diarrhea
Information about Protracted diarrhea....
Recurrent fever
Periodic (episodic or recurrent) bouts of fever....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
Skin rash
A red eruption of the skin....
Tests used to investigate Omenn syndrome
Healthcare providers may order these tests when evaluating Omenn syndrome. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Conditions with overlapping symptoms
These conditions share symptoms with Omenn syndrome, which is why a clinical evaluation is important.
Aicardi-Goutieres syndrome 7
Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the IFIH1 gene....
Netherton syndrome
Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a dis...
Pediatric systemic lupus erythematosus
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immunodeficiency 131
immunodeficiency 131 is a medical condition that may be associated with various symptoms and signs....
immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy
immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy is a medical condition th...
immunodeficiency 91 and hyperinflammation
An autosomal recessive immunodeficiency caused by a variation in the ZNFX1 gene, characterized by severe infec...
Frequently Asked Questions
What is Omenn syndrome?
Omenn syndrome is a health condition described in medical literature. An inflammatory condition characterized by erythroderma, desquamation, alopecia, chronic diarrhea, failure to thrive, lymphadenopathy, and hepatosplenomegaly, associated with severe combined immunodeficiency (SCID).
What are the symptoms of Omenn syndrome?
Omenn syndrome is associated with 12 symptoms in the medical literature we index, including Alopecia, Alopecia of scalp, Diarrhea, Edema, Failure to thrive, Generalized lymphadenopathy. Symptoms vary widely between individuals.
How is Omenn syndrome diagnosed or investigated?
A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with Omenn syndrome include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.
Is SymptomDatabase.com diagnosing me?
No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have Omenn syndrome, please discuss your symptoms with a qualified healthcare provider.