Melnick-Needles syndrome
A otopalatodigital syndrome spectrum disorder and is associated with a short stature, facial dysmorphism, osseous abnormalities involving the majority of the axial and appendicular skeleton resulting in impaired speech and masticatory problems.
Also known as: Melnick Needles Syndrome, Melnick-Needles osteodysplasty, Melnick-Needles syndrome, Melnick-Needles syndrome, X-linked dominant, MNS.
Category: General
Symptoms associated with Melnick-Needles syndrome
The following symptoms have been associated with Melnick-Needles syndrome in medical literature. Not everyone experiences the same symptoms.
Arthralgia
Joint pain....
Bilateral sensorineural hearing impairment
A form of sensorineural hearing impairment that affects both ears....
Failure to thrive
Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm....
Gastroesophageal reflux
A condition in which the stomach contents leak backwards from the stomach into the esophagus through the lower...
Hoarse voice
Hoarseness refers to a change in the pitch or quality of the voice, with the voice sounding weak, very breathy...
Prolonged neonatal jaundice
Neonatal jaundice refers to a yellowing of the skin and other tissues of a newborn infant as a result of incre...
Vomiting
Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic...
Weight loss
Reduction of total body weight....
Tests used to investigate Melnick-Needles syndrome
Healthcare providers may order these tests when evaluating Melnick-Needles syndrome. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Conditions with overlapping symptoms
These conditions share symptoms with Melnick-Needles syndrome, which is why a clinical evaluation is important.
Brucellosis
Brucellosis is a medical condition that may be associated with various symptoms and signs....
Infantile Krabbe disease
Infantile Krabbe disease is a medical condition that may be associated with various symptoms and signs....
RNU5B-1 related neurodevelopmental disorder with seizures and joint laxity
A neurodevelopmental disorder in which the cause of the disease is a variation in RNU5B-1 gene and is characte...
Wilson disease
Wilson disease is a medical condition that may be associated with various symptoms and signs....
developmental delay, impaired speech, and behavioral abnormalities
developmental delay, impaired speech, and behavioral abnormalities is a medical condition that may be associat...
mitochondrial DNA depletion syndrome 6 (hepatocerebral type)
mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a medical condition that may be associated wit...
Frequently Asked Questions
What is Melnick-Needles syndrome?
Melnick-Needles syndrome is a health condition described in medical literature. A otopalatodigital syndrome spectrum disorder and is associated with a short stature, facial dysmorphism, osseous abnormalities involving the majority of the axial and appendicular skeleton resulting in impaired speech and masticatory problems.
What are the symptoms of Melnick-Needles syndrome?
Melnick-Needles syndrome is associated with 8 symptoms in the medical literature we index, including Arthralgia, Bilateral sensorineural hearing impairment, Failure to thrive, Gastroesophageal reflux, Hoarse voice, Prolonged neonatal jaundice. Symptoms vary widely between individuals.
How is Melnick-Needles syndrome diagnosed or investigated?
A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with Melnick-Needles syndrome include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.
Is SymptomDatabase.com diagnosing me?
No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have Melnick-Needles syndrome, please discuss your symptoms with a qualified healthcare provider.