hereditary spastic paraplegia 7
Autosomal recessive spastic paraplegia type 7 is a form of hereditary spastic paraplegia characterized by an onset usually in adulthood (but ranging from 10-72 years) of progressive bilateral lower limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus, decreased hearing, scoliosis, pes cavus, motor and sensory neuropathy, amyotrophy, blepharoptosis and ophthalmoplegia.
Also known as: SPG7, SPG7 hereditary spastic paraplegia, hereditary spastic paraplegia 7, hereditary spastic paraplegia caused by mutation in SPG7, hereditary spastic paraplegia type 7, spastic paraplegia type 7, hereditary spastic paraplegia paraplegin type, spastic paraplegia 7, spastic paraplegia 7, autosomal recessive.
Category: General
Symptoms associated with hereditary spastic paraplegia 7
The following symptoms have been associated with hereditary spastic paraplegia 7 in medical literature. Not everyone experiences the same symptoms.
Dysphagia
Difficulty in swallowing....
Hearing impairment
A decreased magnitude of the sensory perception of sound....
Lower limb muscle weakness
Weakness of the muscles of the legs....
Memory impairment
An impairment of memory as manifested by a reduced ability to remember things such as dates and names, and inc...
Muscle weakness
Reduced strength of muscles....
Upper limb muscle weakness
Weakness of the muscles of the arms....
Urinary incontinence
Loss of the ability to control the urinary bladder leading to involuntary urination....
Tests used to investigate hereditary spastic paraplegia 7
Healthcare providers may order these tests when evaluating hereditary spastic paraplegia 7. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Conditions with overlapping symptoms
These conditions share symptoms with hereditary spastic paraplegia 7, which is why a clinical evaluation is important.
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Meningioma
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Poliomyelitis
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Tay-Sachs disease
Tay-Sachs disease is a medical condition that may be associated with various symptoms and signs....
mitochondrial DNA depletion syndrome 6 (hepatocerebral type)
mitochondrial DNA depletion syndrome 6 (hepatocerebral type) is a medical condition that may be associated wit...
multiple mitochondrial dysfunctions syndrome 9b
A mitochondrial dysfunction syndrome in which the cause of the disease is a mutation in the FDXR gene. It is c...
Frequently Asked Questions
What is hereditary spastic paraplegia 7?
hereditary spastic paraplegia 7 is a health condition described in medical literature. Autosomal recessive spastic paraplegia type 7 is a form of hereditary spastic paraplegia characterized by an onset usually in adulthood (but ranging from 10-72 years) of progressive bilateral lower limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus, decreased hearing, scoliosis, pes cavus, motor and sensory neuropathy, amyotrophy, blepharoptosis and ophthalmoplegia.
What are the symptoms of hereditary spastic paraplegia 7?
hereditary spastic paraplegia 7 is associated with 7 symptoms in the medical literature we index, including Dysphagia, Hearing impairment, Lower limb muscle weakness, Memory impairment, Muscle weakness, Upper limb muscle weakness. Symptoms vary widely between individuals.
How is hereditary spastic paraplegia 7 diagnosed or investigated?
A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with hereditary spastic paraplegia 7 include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.
Is SymptomDatabase.com diagnosing me?
No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have hereditary spastic paraplegia 7, please discuss your symptoms with a qualified healthcare provider.