Late-onset proximal muscle weakness
Lack of strength of the proximal musculature occurring late in the clinical course.
Conditions associated with late-onset proximal muscle weakness
The following conditions have been associated with late-onset proximal muscle weakness in medical literature. This is informational and not a diagnosis.
Thyrotoxic periodic paralysis
Thyrotoxic periodic paralysis is a medical condition that may be associated with various symptoms and signs....
myofibrillar myopathy 1
A rare genetic skeletal muscle disease characterized by abnormal chimeric aggregates of desmin and other cytos...
myofibrillar myopathy 2
Any autosomal dominant distal myopathy in which the cause of the disease is a mutation in the CRYAB gene....
Tests providers may use to investigate late-onset proximal muscle weakness
When investigating late-onset proximal muscle weakness, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside late-onset proximal muscle weakness
Constipation
Infrequent or difficult evacuation of feces....
Diarrhea
Abnormally increased frequency (usually defined as three or more) loose or watery bowel movements a day....
Dysphagia
Difficulty in swallowing....
Lower limb muscle weakness
Weakness of the muscles of the legs....
Tremor
An unintentional, oscillating to-and-fro muscle movement about a joint axis....
Weight loss
Reduction of total body weight....
When to seek care
Seek care from a qualified healthcare provider if late-onset proximal muscle weakness is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom late-onset proximal muscle weakness mean?
Late-onset proximal muscle weakness is a health sign or symptom described in medical literature. Lack of strength of the proximal musculature occurring late in the clinical course.
Which conditions are associated with late-onset proximal muscle weakness?
Late-onset proximal muscle weakness has been reported in association with 3 conditions in the medical literature we index, including Thyrotoxic periodic paralysis, myofibrillar myopathy 1, myofibrillar myopathy 2. These associations do not mean you have any of these conditions.
Should I see a doctor about late-onset proximal muscle weakness?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.