Myoclonic seizure

A myoclonic seizure is a type of motor seizure characterized by sudden, brief (<100 ms) involuntary single or multiple contraction of muscles or muscle groups of variable topography (axial, proximal limb, distal). Myoclonus is less regularly repetitive and less sustained than is clonus.

Not sure what myoclonic seizure might be related to? See the lab tests that healthcare providers may use to investigate myoclonic seizure, and the conditions they help explore.
Explore relevant lab tests
Associations

Conditions associated with myoclonic seizure

The following conditions have been associated with myoclonic seizure in medical literature. This is informational and not a diagnosis.

CDKL5-deficiency disorder

CDKL5-deficiency disorder is a medical condition that may be associated with various symptoms and signs....

General

Developmental and epileptic encephalopathy 122

Developmental and epileptic encephalopathy 122 is a medical condition that may be associated with various symp...

General

Dursun-Ozgul neurodevelopmental syndrome

Dursun-Ozgul neurodevelopmental syndrome is a medical condition that may be associated with various symptoms a...

General

Epilepsy of infancy with migrating focal seizures

Epilepsy of infancy with migrating focal seizures is a medical condition that may be associated with various s...

General

Houge-Janssens syndrome 4

Houge-Janssens syndrome 4 is a medical condition that may be associated with various symptoms and signs....

General

Jeffries-Lakhani neurodevelopmental syndrome

Jeffries-Lakhani neurodevelopmental syndrome is a medical condition that may be associated with various sympto...

General

Juvenile absence epilepsy

Juvenile absence epilepsy is a medical condition that may be associated with various symptoms and signs....

General

Karayol-Borroto-Haghshenas neurodevelopmental syndrome

Karayol-Borroto-Haghshenas neurodevelopmental syndrome is a medical condition that may be associated with vari...

General

New-onset refractory status epilepticus

New-onset refractory status epilepticus is a medical condition that may be associated with various symptoms an...

General

Sandhoff disease

A lysosomal disorder from the GM2 gangliosidosis family, caused by biallelic pathogenic variants in the HEXB g...

General

Stolerman neurodevelopmental syndrome

Stolerman neurodevelopmental syndrome is a medical condition that may be associated with various symptoms and ...

General

developmental and epileptic encephalopathy 100

developmental and epileptic encephalopathy 100 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 103

developmental and epileptic encephalopathy 103 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 108

developmental and epileptic encephalopathy 108 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 109

developmental and epileptic encephalopathy 109 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 112

developmental and epileptic encephalopathy 112 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 114

developmental and epileptic encephalopathy 114 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 116

developmental and epileptic encephalopathy 116 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 118

developmental and epileptic encephalopathy 118 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 119

A developmental and epileptic encephalopathy caused by the variants in the RNU2-2 gene, in which most reported...

General

developmental and epileptic encephalopathy 120

developmental and epileptic encephalopathy 120 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy 6B

developmental and epileptic encephalopathy 6B is a medical condition that may be associated with various sympt...

General

developmental and epileptic encephalopathy 91

developmental and epileptic encephalopathy 91 is a medical condition that may be associated with various sympt...

General

developmental and epileptic encephalopathy, 19

Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the GABRA1 gen...

General

developmental and epileptic encephalopathy, 24

Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the HCN1 gene....

General

developmental and epileptic encephalopathy, 31A

Any developmental and epileptic encephalopathy in which the cause of the disease is a heterozygous mutation in...

General

developmental and epileptic encephalopathy, 51

Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the MDH2 gene....

General

developmental and epileptic encephalopathy, 56

developmental and epileptic encephalopathy, 56 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy, 63

developmental and epileptic encephalopathy, 63 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy, 66

developmental and epileptic encephalopathy, 66 is a medical condition that may be associated with various symp...

General

developmental and epileptic encephalopathy, 6A

Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the SCN1A gene...

General

developmental and epileptic encephalopathy, 74

developmental and epileptic encephalopathy, 74 is a medical condition that may be associated with various symp...

General

developmental delay with or without epilepsy

developmental delay with or without epilepsy is a medical condition that may be associated with various sympto...

General

epilepsy, early-onset, 3, with or without developmental delay

epilepsy, early-onset, 3, with or without developmental delay is a medical condition that may be associated wi...

General

hyperphosphatasia with intellectual disability syndrome 3

Any hyperphosphatasia-intellectual disability syndrome in which the cause of the disease is a mutation in the ...

General

intellectual disability, autosomal dominant 42

Any autosomal dominant intellectual disability in which the cause of the disease is a heterozygous mutation in...

General

intellectual disability, autosomal dominant 43

Any autosomal dominant non-syndromic intellectual disability in which the cause of the disease is a mutation i...

General

intellectual disability, autosomal dominant 55, with seizures

intellectual disability, autosomal dominant 55, with seizures is a medical condition that may be associated wi...

General

lissencephaly 10

lissencephaly 10 is a medical condition that may be associated with various symptoms and signs....

General

microcephaly, epilepsy, and diabetes syndrome 1

microcephaly, epilepsy, and diabetes syndrome 1 is a medical condition that may be associated with various sym...

General

Tests

Tests providers may use to investigate myoclonic seizure

When investigating myoclonic seizure, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.

CBC with Differential

Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...

Sample: Blood

Comprehensive Metabolic Panel (CMP)

Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...

Sample: Blood

Fasting Glucose

Measures blood sugar after fasting to screen for diabetes and prediabetes....

Sample: Blood

Ferritin

Measures iron stores in the body....

Sample: Blood

Folate

Measures folate levels to help evaluate anemia and pregnancy health....

Sample: Blood

Hemoglobin A1c (HbA1c)

Reflects average blood sugar over the past 2-3 months....

Sample: Blood

Iron Panel

Measures iron, TIBC, transferrin saturation, and ferritin....

Sample: Blood

Urinalysis

Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....

Sample: Urine

Vitamin B12

Detects B12 deficiency which can cause anemia and neurological symptoms....

Sample: Blood

Related

Symptoms commonly seen alongside myoclonic seizure

When to seek care

Seek care from a qualified healthcare provider if myoclonic seizure is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.

FAQ

Frequently Asked Questions

What does the symptom myoclonic seizure mean?

Myoclonic seizure is a health sign or symptom described in medical literature. A myoclonic seizure is a type of motor seizure characterized by sudden, brief (<100 ms) involuntary single or multiple contraction of muscles or muscle groups of variable topography (axial, proximal limb, distal). Myoclonus is less regularly repetitive and less sustained than is clonus.

Which conditions are associated with myoclonic seizure?

Myoclonic seizure has been reported in association with 57 conditions in the medical literature we index, including CDKL5-deficiency disorder, Developmental and epileptic encephalopathy 122, Dursun-Ozgul neurodevelopmental syndrome, Epilepsy of infancy with migrating focal seizures, Houge-Janssens syndrome 4. These associations do not mean you have any of these conditions.

Should I see a doctor about myoclonic seizure?

You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.

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