Limb-girdle muscle weakness
Weakness of the limb-girdle muscles (also known as the pelvic and shoulder girdles), that is, lack of strength of the muscles around the shoulders and the pelvis.
Also called: Limb girdle weakness, Muscle weakness, limb-girdle, Muscular weakness, limb-girdle.
Conditions associated with limb-girdle muscle weakness
The following conditions have been associated with limb-girdle muscle weakness in medical literature. This is informational and not a diagnosis.
Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency
Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency is a medical condition that m...
Alpha-B crystallin-related late-onset myopathy
Alpha-B crystallin-related late-onset myopathy is a medical condition that may be associated with various symp...
Autosomal dominant Charcot-Marie-Tooth disease type 2Z
Autosomal dominant Charcot-Marie-Tooth disease type 2Z is a medical condition that may be associated with vari...
Bethlem muscular dystrophy
Bethlem muscular dystrophy is a medical condition that may be associated with various symptoms and signs....
Bethlem myopathy 1A
Bethlem myopathy 1A is a medical condition that may be associated with various symptoms and signs....
Congenital myasthenic syndrome
Congenital myasthenic syndrome is a medical condition that may be associated with various symptoms and signs....
Dermatomyositis
Dermatomyositis is a medical condition that may be associated with various symptoms and signs....
Emery-Dreifuss muscular dystrophy 2, autosomal dominant
Emery-Dreifuss muscular dystrophy inherited in an autosomal dominant pattern and caused by mutations in the LM...
Facioscapulohumeral dystrophy
Facioscapulohumeral dystrophy is a medical condition that may be associated with various symptoms and signs....
Glycogen storage disease due to liver and muscle phosphorylase kinase deficiency
Glycogen storage disease due to liver and muscle phosphorylase kinase deficiency is a medical condition that m...
Late-onset distal myopathy, Markesbery-Griggs type
Late-onset distal myopathy, Markesbery-Griggs type is a medical condition that may be associated with various ...
Oculopharyngeal muscular dystrophy
Oculopharyngeal muscular dystrophy is a medical condition that may be associated with various symptoms and sig...
Plectin-related limb-girdle muscular dystrophy R17
Plectin-related limb-girdle muscular dystrophy R17 is a medical condition that may be associated with various ...
Presynaptic congenital myasthenic syndromes
Presynaptic congenital myasthenic syndromes is a medical condition that may be associated with various symptom...
Typical nemaline myopathy
Typical nemaline myopathy is a medical condition that may be associated with various symptoms and signs....
myofibrillar myopathy 2
Any autosomal dominant distal myopathy in which the cause of the disease is a mutation in the CRYAB gene....
myopathy, myofibrillar, 13, with rimmed vacuoles
A rare genetic neuromuscular disease caused by a mutation in HSPB8 gene, characterized by length-dependent axo...
polyglucosan body myopathy type 2
Any polyglucosan body myopathy in which the cause of the disease is a mutation in the GYG1 gene....
Tests providers may use to investigate limb-girdle muscle weakness
When investigating limb-girdle muscle weakness, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside limb-girdle muscle weakness
Depression
Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover from these m...
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if limb-girdle muscle weakness is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom limb-girdle muscle weakness mean?
Limb-girdle muscle weakness is a health sign or symptom described in medical literature. Weakness of the limb-girdle muscles (also known as the pelvic and shoulder girdles), that is, lack of strength of the muscles around the shoulders and the pelvis.
Which conditions are associated with limb-girdle muscle weakness?
Limb-girdle muscle weakness has been reported in association with 18 conditions in the medical literature we index, including Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency, Alpha-B crystallin-related late-onset myopathy, Autosomal dominant Charcot-Marie-Tooth disease type 2Z, Bethlem muscular dystrophy, Bethlem myopathy 1A. These associations do not mean you have any of these conditions.
Should I see a doctor about limb-girdle muscle weakness?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.