Insomnia
Persistent difficulty in starting or maintaining sleep, or waking up earlier than desired, despite having adequate opportunities and conditions for sleep.
Also called: Difficulty staying or falling asleep, Inability to sleep.
Conditions associated with insomnia
The following conditions have been associated with insomnia in medical literature. This is informational and not a diagnosis.
3-methylcrotonyl-CoA carboxylase 1 deficiency
Any 3-methylcrotonyl-CoA carboxylase deficiency in which the cause of the disease is a mutation in the MCCC1 g...
Acute intermittent porphyria
Acute intermittent porphyria is a medical condition that may be associated with various symptoms and signs....
African trypanosomiasis
African trypanosomiasis is a medical condition that may be associated with various symptoms and signs....
Anxiety Disorder
A group of mental health conditions characterized by excessive worry, fear, or nervousness that interferes wit...
Anxiety and Panic
Persistent anxiety and panic symptoms that affect daily function and well-being....
Arachnoid cyst
Arachnoid cyst is a medical condition that may be associated with various symptoms and signs....
Arboleda-Tham syndrome
Arboleda-Tham syndrome is a medical condition that may be associated with various symptoms and signs....
Citrullinemia type II
Citrullinemia type II is a medical condition that may be associated with various symptoms and signs....
Coproporphyria
Coproporphyria is a medical condition that may be associated with various symptoms and signs....
Cushing syndrome due to ectopic ACTH secretion
Cushing syndrome due to ectopic ACTH secretion is a medical condition that may be associated with various symp...
Depression
A common but serious mood disorder causing persistent sadness, loss of interest, and changes in sleep, appetit...
Epilepsy with eyelid myoclonia
Epilepsy with eyelid myoclonia is a medical condition that may be associated with various symptoms and signs....
Essential thrombocythemia
Essential thrombocythemia is a medical condition that may be associated with various symptoms and signs....
Fatal familial insomnia
Fatal familial insomnia is a medical condition that may be associated with various symptoms and signs....
Gaisböck syndrome
Gaisböck syndrome is a medical condition that may be associated with various symptoms and signs....
Generalized Anxiety Disorder
Persistent, excessive worry about everyday situations that is difficult to control and interferes with daily l...
Gitelman syndrome
Gitelman syndrome is a medical condition that may be associated with various symptoms and signs....
Hemorrhagic fever-renal syndrome
Hemorrhagic fever-renal syndrome is a medical condition that may be associated with various symptoms and signs...
Houge-Janssens syndrome 4
Houge-Janssens syndrome 4 is a medical condition that may be associated with various symptoms and signs....
Huntington disease
Huntington disease is a medical condition that may be associated with various symptoms and signs....
Hyperammonemia due to N-acetylglutamate synthase deficiency
Hyperammonemia due to N-acetylglutamate synthase deficiency is a medical condition that may be associated with...
Hyperthyroidism
A condition in which the thyroid gland produces too much thyroid hormone, speeding up metabolism and causing w...
Inherited Creutzfeldt-Jakob disease
Inherited Creutzfeldt-Jakob disease is a medical condition that may be associated with various symptoms and si...
Insomnia
Difficulty falling asleep, staying asleep, or getting restful sleep despite adequate opportunity, affecting da...
Insulinoma
Insulinoma is a medical condition that may be associated with various symptoms and signs....
Lead poisoning
Lead poisoning is a medical condition that may be associated with various symptoms and signs....
Mercury poisoning
Mercury poisoning is a medical condition that may be associated with various symptoms and signs....
NMDA receptor encephalitis
NMDA receptor encephalitis is a medical condition that may be associated with various symptoms and signs....
Pediatric-onset Graves disease
Pediatric-onset Graves disease is a medical condition that may be associated with various symptoms and signs....
Post Traumatic Stress Disorder
A condition that develops after experiencing or witnessing a traumatic event, causing intrusive memories, avoi...
Progeria-short stature-pigmented nevi syndrome
Progeria-short stature-pigmented nevi syndrome is a medical condition that may be associated with various symp...
RNU5B-1 related neurodevelopmental disorder with seizures and joint laxity
A neurodevelopmental disorder in which the cause of the disease is a variation in RNU5B-1 gene and is characte...
Rabies
Rabies is a medical condition that may be associated with various symptoms and signs....
Restless Legs Syndrome
An urge to move the legs, usually at night, often accompanied by uncomfortable sensations that improve with mo...
Sandhoff disease, juvenile form
Sandhoff disease, juvenile form is a medical condition that may be associated with various symptoms and signs....
Serotonin syndrome
Serotonin syndrome is a medical condition that may be associated with various symptoms and signs....
Typhoid
Typhoid is a medical condition that may be associated with various symptoms and signs....
Williams syndrome
Williams syndrome is a medical condition that may be associated with various symptoms and signs....
Wilson disease
Wilson disease is a medical condition that may be associated with various symptoms and signs....
Wilson disease
A very rare inherited multisystemic disease presenting non-specific neurological, hepatic, psychiatric or osse...
Tests providers may use to investigate insomnia
When investigating insomnia, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Calcium
Measures calcium levels to evaluate bone, kidney, and parathyroid health....
Cbc, Cmp, Ua, Thyroid, & Lipid Health Tests
Our standard health test panel includes thyroid testing, a CBC, CMP, Urinalysis, & Lipid Panel. These lab test...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Free T3
Measures triiodothyronine, a thyroid hormone involved in metabolism....
Free T4
Measures the active form of thyroxine to help evaluate thyroid function....
Reverse T3 Test
The Reverse T3 (rT3) blood test is used to help determine if an individual has "nonthyroidal illness synd...
Thyroid Panel
Comprehensive thyroid testing including TSH, free T4, and free T3....
Thyroid Peroxidase Antibodies (TPO)
Detects antibodies associated with autoimmune thyroid disease....
Thyroid Stimulating Hormone (TSH)
Screens for thyroid disorders such as hypothyroidism and hyperthyroidism....
Symptoms commonly seen alongside insomnia
Daytime Sleepiness
Excessive sleepiness during the day despite getting enough sleep at night, which can be a sign of sleep apnea ...
Difficulty Concentrating
Trouble focusing or paying attention, which can be caused by stress, sleep problems, depression, or other cond...
Excessive Sweating
Sweating more than is needed to regulate body temperature, which can accompany fever, anxiety, hypoglycemia, o...
Irritability
Easily annoyed or frustrated mood, which can be caused by stress, sleep problems, hormonal changes, or mood di...
Low Mood
Persistent sadness, emptiness, or hopelessness, which is a core symptom of depression....
Restlessness
An inability to sit still or relax, which can be related to anxiety, ADHD, or other conditions....
When to seek care
Seek care from a qualified healthcare provider if insomnia is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom insomnia mean?
Insomnia is a health sign or symptom described in medical literature. Persistent difficulty in starting or maintaining sleep, or waking up earlier than desired, despite having adequate opportunities and conditions for sleep.
Which conditions are associated with insomnia?
Insomnia has been reported in association with 46 conditions in the medical literature we index, including 3-methylcrotonyl-CoA carboxylase 1 deficiency, Acute intermittent porphyria, African trypanosomiasis, Anxiety Disorder, Anxiety and Panic. These associations do not mean you have any of these conditions.
Should I see a doctor about insomnia?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.