Generalized-onset seizure
A generalized-onset seizure is a type of seizure originating at some point within, and rapidly engaging, bilaterally distributed networks. The networks may include cortical and subcortical structures but not necessarily the entire cortex.
Also called: Generalised onset seizure, Generalised seizures, Generalised-onset seizure, Generalized onset seizure, Generalized seizures, Generalized-onset seizures, Primary generalised seizure, Primary generalized seizure.
Conditions associated with generalized-onset seizure
The following conditions have been associated with generalized-onset seizure in medical literature. This is informational and not a diagnosis.
Bilateral generalized polymicrogyria
Bilateral generalized polymicrogyria is a medical condition that may be associated with various symptoms and s...
Bilateral polymicrogyria
Bilateral polymicrogyria is a medical condition that may be associated with various symptoms and signs....
Christianson syndrome
Christianson syndrome is a medical condition that may be associated with various symptoms and signs....
Cysticercosis
Cysticercosis is a medical condition that may be associated with various symptoms and signs....
Dursun-Ozgul neurodevelopmental syndrome
Dursun-Ozgul neurodevelopmental syndrome is a medical condition that may be associated with various symptoms a...
Epilepsy with auditory features
Epilepsy with auditory features is a medical condition that may be associated with various symptoms and signs....
Genetic epilepsy with febrile seizure plus
Genetic epilepsy with febrile seizure plus is a medical condition that may be associated with various symptoms...
Houge-Janssens syndrome 4
Houge-Janssens syndrome 4 is a medical condition that may be associated with various symptoms and signs....
Hyperprolinemia type 2
Hyperprolinemia type 2 is a medical condition that may be associated with various symptoms and signs....
Isolated focal cortical dysplasia
Isolated focal cortical dysplasia is a medical condition that may be associated with various symptoms and sign...
Jaberi-Elahi syndrome
Jaberi-Elahi syndrome is a medical condition that may be associated with various symptoms and signs....
Jeffries-Lakhani neurodevelopmental syndrome
Jeffries-Lakhani neurodevelopmental syndrome is a medical condition that may be associated with various sympto...
Juvenile absence epilepsy
Juvenile absence epilepsy is a medical condition that may be associated with various symptoms and signs....
Kleefstra syndrome 1
An autosomal dominant non-syndromic intellectual disability that has material basis in an autosomal dominant m...
Mitochondrial DNA depletion syndrome, myopathic form
Mitochondrial DNA depletion syndrome, myopathic form is a medical condition that may be associated with variou...
NMDA receptor encephalitis
NMDA receptor encephalitis is a medical condition that may be associated with various symptoms and signs....
Niemann-Pick disease type C
Niemann-Pick disease type C is a medical condition that may be associated with various symptoms and signs....
Noonan syndrome 13
Noonan syndrome 13 is a medical condition that may be associated with various symptoms and signs....
Ogden syndrome
Ogden syndrome is a rare, genetic progeroid syndrome characterized by a variable phenotype including postnatal...
PMM2-congenital disorder of glycosylation
The most frequent form of congenital disorder of N-glycosylation and is characterized by cerebellar dysfunctio...
Pan-Chung-Bellen syndrome
Pan-Chung-Bellen syndrome is a medical condition that may be associated with various symptoms and signs....
Pitt-Hopkins like syndrome 1
Pitt-Hopkins like syndrome 1 is a medical condition that may be associated with various symptoms and signs....
Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations is a medical condition that...
Spinocerebellar ataxia type 10
Spinocerebellar ataxia type 10 is a medical condition that may be associated with various symptoms and signs....
Steroid-responsive encephalopathy associated with autoimmune thyroiditis
Steroid-responsive encephalopathy associated with autoimmune thyroiditis is a medical condition that may be as...
Tick-borne encephalitis
Tick-borne encephalitis is a medical condition that may be associated with various symptoms and signs....
ZTTK syndrome
ZTTK syndrome is a medical condition that may be associated with various symptoms and signs....
basal ganglia calcification, idiopathic, 11, autosomal recessive
basal ganglia calcification, idiopathic, 11, autosomal recessive is a medical condition that may be associated...
branched-chain keto acid dehydrogenase kinase deficiency
A rare disorder of branched-chain amino acid metabolism characterized by childhood-onset epilepsy, autism and ...
combined oxidative phosphorylation deficiency 54
combined oxidative phosphorylation deficiency 54 is a medical condition that may be associated with various sy...
congenital lactic acidosis, Saguenay-Lac-Saint-Jean type
Saguenay-Lac-St. Jean (SLSJ) type congenital lactic acidosis, a French Canadian form of Leigh syndrome, is a m...
developmental and epileptic encephalopathy 116
developmental and epileptic encephalopathy 116 is a medical condition that may be associated with various symp...
developmental and epileptic encephalopathy 119
A developmental and epileptic encephalopathy caused by the variants in the RNU2-2 gene, in which most reported...
developmental and epileptic encephalopathy, 2
Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the CDKL5 gene...
developmental and epileptic encephalopathy, 63
developmental and epileptic encephalopathy, 63 is a medical condition that may be associated with various symp...
leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy
leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy is a medical condition that may be...
lissencephaly 10
lissencephaly 10 is a medical condition that may be associated with various symptoms and signs....
methylcobalamin deficiency type cblG
Methylcobalamin deficiency cbl G type is a rare condition that occurs when the body is unable to process certa...
microcephaly, epilepsy, and diabetes syndrome 1
microcephaly, epilepsy, and diabetes syndrome 1 is a medical condition that may be associated with various sym...
mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
Mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria is characterized by ...
Tests providers may use to investigate generalized-onset seizure
When investigating generalized-onset seizure, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Fasting Glucose
Measures blood sugar after fasting to screen for diabetes and prediabetes....
Hemoglobin A1c (HbA1c)
Reflects average blood sugar over the past 2-3 months....
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside generalized-onset seizure
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if generalized-onset seizure is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom generalized-onset seizure mean?
Generalized-onset seizure is a health sign or symptom described in medical literature. A generalized-onset seizure is a type of seizure originating at some point within, and rapidly engaging, bilaterally distributed networks. The networks may include cortical and subcortical structures but not necessarily the entire cortex.
Which conditions are associated with generalized-onset seizure?
Generalized-onset seizure has been reported in association with 52 conditions in the medical literature we index, including Bilateral generalized polymicrogyria, Bilateral polymicrogyria, Christianson syndrome, Cysticercosis, Dursun-Ozgul neurodevelopmental syndrome. These associations do not mean you have any of these conditions.
Should I see a doctor about generalized-onset seizure?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.