Generalised tonic-clonic seizure without focal onset
A bilateral tonic-clonic seizure with generalized onset is a type of bilateral tonic-clonic seizure characterized by generalized onset; these seizures rapidly engage networks in both hemispheres at the start of the seizure.
Also called: Bilateral tonic-clonic seizure with generalised onset, Generalised tonic-clonic seizure without focal onset, Generalised tonic-clonic seizure without partial onset, Generalised tonic-clonic seizures without focal onset, Generalised-onset tonic-clonic seizure, Generalized tonic-clonic seizure without focal onset, Generalized tonic-clonic seizure without partial onset, Generalized tonic-clonic seizures without focal onset, Generalized-onset tonic-clonic seizure, Primarily generalised tonic-clonic seizures.
Conditions associated with generalised tonic-clonic seizure without focal onset
The following conditions have been associated with generalised tonic-clonic seizure without focal onset in medical literature. This is informational and not a diagnosis.
3-methylcrotonyl-CoA carboxylase 1 deficiency
Any 3-methylcrotonyl-CoA carboxylase deficiency in which the cause of the disease is a mutation in the MCCC1 g...
Angelman syndrome due to paternal uniparental disomy of chromosome 15
Angelman syndrome due to paternal uniparental disomy of chromosome 15 is a medical condition that may be assoc...
CTCF-related neurodevelopmental disorder
A rare, genetic, neurodevelopmental disorder characterized by global developmental delay, borderline to severe...
Coffin-Siris syndrome 6
Any Coffin-Siris syndrome in which the cause of the disease is a mutation in the ARID2 gene....
Developmental and epileptic encephalopathy 122
Developmental and epileptic encephalopathy 122 is a medical condition that may be associated with various symp...
Dursun-Ozgul neurodevelopmental syndrome
Dursun-Ozgul neurodevelopmental syndrome is a medical condition that may be associated with various symptoms a...
Epilepsy with eyelid myoclonia
Epilepsy with eyelid myoclonia is a medical condition that may be associated with various symptoms and signs....
Epilepsy with myoclonic-atonic seizures
Epilepsy with myoclonic-atonic seizures is a medical condition that may be associated with various symptoms an...
Familial infantile myoclonic epilepsy
Familial infantile myoclonic epilepsy is a medical condition that may be associated with various symptoms and ...
GM1 gangliosidosis
GM1 gangliosidosis is a medical condition that may be associated with various symptoms and signs....
Glycogen storage disease 0, muscle
Glycogen storage disease 0, muscle is a medical condition that may be associated with various symptoms and sig...
Jaberi-Elahi syndrome
Jaberi-Elahi syndrome is a medical condition that may be associated with various symptoms and signs....
Jeffries-Lakhani neurodevelopmental syndrome
Jeffries-Lakhani neurodevelopmental syndrome is a medical condition that may be associated with various sympto...
Karayol-Borroto-Haghshenas neurodevelopmental syndrome
Karayol-Borroto-Haghshenas neurodevelopmental syndrome is a medical condition that may be associated with vari...
Landau-Kleffner syndrome
Landau-Kleffner syndrome is a medical condition that may be associated with various symptoms and signs....
Rasmussen subacute encephalitis
Rasmussen subacute encephalitis is a medical condition that may be associated with various symptoms and signs....
Spinal muscular atrophy-progressive myoclonic epilepsy syndrome
Spinal muscular atrophy-progressive myoclonic epilepsy syndrome is a medical condition that may be associated ...
White-Sutton syndrome
White-Sutton syndrome is a medical condition that may be associated with various symptoms and signs....
congenital disorder of glycosylation, type IIcc
congenital disorder of glycosylation, type IIcc is a medical condition that may be associated with various sym...
developmental and epileptic encephalopathy 108
developmental and epileptic encephalopathy 108 is a medical condition that may be associated with various symp...
developmental and epileptic encephalopathy 120
developmental and epileptic encephalopathy 120 is a medical condition that may be associated with various symp...
developmental and epileptic encephalopathy 121
developmental and epileptic encephalopathy 121 is a medical condition that may be associated with various symp...
developmental and epileptic encephalopathy, 19
Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the GABRA1 gen...
developmental and epileptic encephalopathy, 9
Female restricted epilepsy with intellectual disability is a rare X-linked epilepsy syndrome characterized by ...
leukoencephalopathy without lacunae, adult-onset
leukoencephalopathy without lacunae, adult-onset is a medical condition that may be associated with various sy...
mitochondrial DNA depletion syndrome 13
Any mitochondrial DNA depletion syndrome in which the cause of the disease is a mutation in the FBXL4 gene....
neurodevelopmental disorder with ataxia and brain abnormalities
neurodevelopmental disorder with ataxia and brain abnormalities is a medical condition that may be associated ...
neurodevelopmental disorder with dysmorphic facies, brain anomalies, and seizures
neurodevelopmental disorder with dysmorphic facies, brain anomalies, and seizures is a medical condition that ...
neurodevelopmental disorder with early-onset seizures, facial dysmorphism, and behavioral abnormalities
neurodevelopmental disorder with early-onset seizures, facial dysmorphism, and behavioral abnormalities is a m...
neurodevelopmental disorder with growth impairment, quadriparesis, and poor or absent speech
neurodevelopmental disorder with growth impairment, quadriparesis, and poor or absent speech is a medical cond...
neurodevelopmental disorder with hypotonia, epilepsy, and absent speech
A neurodevelopmental syndrome caused by a variation in the UNC13A gene, characterized by hypotonia, epilepsy, ...
neurodevelopmental disorder with seizures and impaired intellectual and language development
neurodevelopmental disorder with seizures and impaired intellectual and language development is a medical cond...
Tests providers may use to investigate generalised tonic-clonic seizure without focal onset
When investigating generalised tonic-clonic seizure without focal onset, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside generalised tonic-clonic seizure without focal onset
Depression
Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover from these m...
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if generalised tonic-clonic seizure without focal onset is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom generalised tonic-clonic seizure without focal onset mean?
Generalised tonic-clonic seizure without focal onset is a health sign or symptom described in medical literature. A bilateral tonic-clonic seizure with generalized onset is a type of bilateral tonic-clonic seizure characterized by generalized onset; these seizures rapidly engage networks in both hemispheres at the start of the seizure.
Which conditions are associated with generalised tonic-clonic seizure without focal onset?
Generalised tonic-clonic seizure without focal onset has been reported in association with 32 conditions in the medical literature we index, including 3-methylcrotonyl-CoA carboxylase 1 deficiency, Angelman syndrome due to paternal uniparental disomy of chromosome 15, CTCF-related neurodevelopmental disorder, Coffin-Siris syndrome 6, Developmental and epileptic encephalopathy 122. These associations do not mean you have any of these conditions.
Should I see a doctor about generalised tonic-clonic seizure without focal onset?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.