Distal lower limb muscle weakness
Reduced strength of the distal musculature of the legs.
Also called: Distal muscle weakness in lower limbs, Muscle weakness, lower limb, distal.
Conditions associated with distal lower limb muscle weakness
The following conditions have been associated with distal lower limb muscle weakness in medical literature. This is informational and not a diagnosis.
Abetalipoproteinemia
Abetalipoproteinemia is a medical condition that may be associated with various symptoms and signs....
Acute transverse myelitis
Acute transverse myelitis is a medical condition that may be associated with various symptoms and signs....
Adenylosuccinate synthetase-like 1-related distal myopathy
Adenylosuccinate synthetase-like 1-related distal myopathy is a medical condition that may be associated with ...
Anoctamin-5-related limb-girdle muscular dystrophy R12
Anoctamin-5-related limb-girdle muscular dystrophy R12 is a medical condition that may be associated with vari...
Autosomal dominant Charcot-Marie-Tooth disease type 2A2
Autosomal dominant Charcot-Marie-Tooth disease type 2A2 is a medical condition that may be associated with var...
Autosomal dominant Charcot-Marie-Tooth disease type 2Y
Autosomal dominant Charcot-Marie-Tooth disease type 2Y is a medical condition that may be associated with vari...
Autosomal dominant Charcot-Marie-Tooth disease type 2Z
Autosomal dominant Charcot-Marie-Tooth disease type 2Z is a medical condition that may be associated with vari...
Autosomal recessive Charcot-Marie-Tooth disease with hoarseness
Autosomal recessive Charcot-Marie-Tooth disease with hoarseness is a medical condition that may be associated ...
Centronuclear myopathy 1
Centronuclear myopathy 1 is a medical condition that may be associated with various symptoms and signs....
Charcot-Marie-Tooth disease X-linked dominant 1
Charcot-Marie-Tooth neuropathy that is inherited in an X-linked manner, and is associated with mutation(s) in ...
Charcot-Marie-Tooth disease axonal type 2C
Autosomal dominant Charcot-Marie-Tooth disease type 2C (CMT2C) is a form of axonal Charcot-Marie-Tooth disease...
Charcot-Marie-Tooth disease type 1E
Charcot-Marie-Tooth disease type 1E is a medical condition that may be associated with various symptoms and si...
Charcot-Marie-Tooth disease type 1F
Charcot-Marie-Tooth disease type 1F is a medical condition that may be associated with various symptoms and si...
Charcot-Marie-Tooth disease type 4B2
Charcot-Marie-Tooth disease type 4B2 is a medical condition that may be associated with various symptoms and s...
Charcot-Marie-Tooth disease, axonal, type 2KK
Charcot-Marie-Tooth disease, axonal, type 2KK is a medical condition that may be associated with various sympt...
Charcot-Marie-tooth disease, axonal, type 2JJ
Charcot-Marie-tooth disease, axonal, type 2JJ is a medical condition that may be associated with various sympt...
Congenital myasthenic syndrome
Congenital myasthenic syndrome is a medical condition that may be associated with various symptoms and signs....
Desminopathy
Desminopathy is a medical condition that may be associated with various symptoms and signs....
Emery-Dreifuss muscular dystrophy 2, autosomal dominant
Emery-Dreifuss muscular dystrophy inherited in an autosomal dominant pattern and caused by mutations in the LM...
FLNC-related handgrip and calf weakness-distal myopathy
FLNC-related handgrip and calf weakness-distal myopathy is a medical condition that may be associated with var...
GMPPB-related limb-girdle muscular dystrophy R19
GMPPB-related limb-girdle muscular dystrophy R19 is a medical condition that may be associated with various sy...
Japanese encephalitis
Japanese encephalitis is a medical condition that may be associated with various symptoms and signs....
Miyoshi myopathy
Miyoshi myopathy is a medical condition that may be associated with various symptoms and signs....
Myopathy, distal, 1
Myopathy, distal, 1 is a medical condition that may be associated with various symptoms and signs....
Oculopharyngodistal myopathy
Oculopharyngodistal myopathy is a medical condition that may be associated with various symptoms and signs....
Plectin-related limb-girdle muscular dystrophy R17
Plectin-related limb-girdle muscular dystrophy R17 is a medical condition that may be associated with various ...
Presynaptic congenital myasthenic syndromes
Presynaptic congenital myasthenic syndromes is a medical condition that may be associated with various symptom...
Proximal spinal muscular atrophy
Proximal spinal muscular atrophy is a medical condition that may be associated with various symptoms and signs...
Spinal fast-flow vascular malformation
Spinal fast-flow vascular malformation is a medical condition that may be associated with various symptoms and...
Von Hippel-Lindau disease
Von Hippel-Lindau disease is a medical condition that may be associated with various symptoms and signs....
amyotrophic lateral sclerosis type 21
Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the MATR3 gene....
congenital myopathy 25
congenital myopathy 25 is a medical condition that may be associated with various symptoms and signs....
congenital myopathy 26
congenital myopathy 26 is a medical condition that may be associated with various symptoms and signs....
multiple mitochondrial dysfunctions syndrome 9b
A mitochondrial dysfunction syndrome in which the cause of the disease is a mutation in the FDXR gene. It is c...
muscular dystrophy, limb-girdle, autosomal recessive 29
muscular dystrophy, limb-girdle, autosomal recessive 29 is a medical condition that may be associated with var...
myopathy, distal, 7, adult-onset, X-linked
myopathy, distal, 7, adult-onset, X-linked is a medical condition that may be associated with various symptoms...
myopathy, myofibrillar, 13, with rimmed vacuoles
A rare genetic neuromuscular disease caused by a mutation in HSPB8 gene, characterized by length-dependent axo...
neuronopathy, distal hereditary motor, autosomal recessive 11, with spasticity
neuronopathy, distal hereditary motor, autosomal recessive 11, with spasticity is a medical condition that may...
neuronopathy, distal hereditary motor, autosomal recessive 7
neuronopathy, distal hereditary motor, autosomal recessive 7 is a medical condition that may be associated wit...
oculopharyngodistal myopathy 5
oculopharyngodistal myopathy 5 is a medical condition that may be associated with various symptoms and signs....
Tests providers may use to investigate distal lower limb muscle weakness
When investigating distal lower limb muscle weakness, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Symptoms commonly seen alongside distal lower limb muscle weakness
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if distal lower limb muscle weakness is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom distal lower limb muscle weakness mean?
Distal lower limb muscle weakness is a health sign or symptom described in medical literature. Reduced strength of the distal musculature of the legs.
Which conditions are associated with distal lower limb muscle weakness?
Distal lower limb muscle weakness has been reported in association with 40 conditions in the medical literature we index, including Abetalipoproteinemia, Acute transverse myelitis, Adenylosuccinate synthetase-like 1-related distal myopathy, Anoctamin-5-related limb-girdle muscular dystrophy R12, Autosomal dominant Charcot-Marie-Tooth disease type 2A2. These associations do not mean you have any of these conditions.
Should I see a doctor about distal lower limb muscle weakness?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.