Bilateral tonic-clonic seizure
A bilateral tonic-clonic seizure is a seizure defined by a tonic (bilateral increased tone, lasting seconds to minutes) and then a clonic (bilateral sustained rhythmic jerking) phase.
Also called: Bilateral convulsive seizures, Generalised convulsion, Generalised tonic-clonic seizure (without specification of onset), Generalized convulsion, Generalized tonic-clonic seizure (without specification of onset), Grand mal, Grand mal seizures, Seizures, tonic-clonic, Tonic-clonic convulsion, Tonic-clonic convulsions.
Conditions associated with bilateral tonic-clonic seizure
The following conditions have been associated with bilateral tonic-clonic seizure in medical literature. This is informational and not a diagnosis.
3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form
3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form is a medical condition that may be associ...
Alternating hemiplegia of childhood
Alternating hemiplegia of childhood is a medical condition that may be associated with various symptoms and si...
Angelman syndrome due to paternal uniparental disomy of chromosome 15
Angelman syndrome due to paternal uniparental disomy of chromosome 15 is a medical condition that may be assoc...
Bilateral generalized polymicrogyria
Bilateral generalized polymicrogyria is a medical condition that may be associated with various symptoms and s...
Bilateral polymicrogyria
Bilateral polymicrogyria is a medical condition that may be associated with various symptoms and signs....
Biotinidase deficiency
Biotinidase deficiency is a medical condition that may be associated with various symptoms and signs....
CDKL5-deficiency disorder
CDKL5-deficiency disorder is a medical condition that may be associated with various symptoms and signs....
CLCN4-related X-linked intellectual disability syndrome
CLCN4-related X-linked intellectual disability syndrome is a medical condition that may be associated with var...
Childhood absence epilepsy
Childhood absence epilepsy is a medical condition that may be associated with various symptoms and signs....
Choreoacanthocytosis
Choreoacanthocytosis is a medical condition that may be associated with various symptoms and signs....
Cocaine intoxication
Cocaine intoxication is a medical condition that may be associated with various symptoms and signs....
Coenzyme Q10 deficiency, primary, 7
Coenzyme Q10 deficiency, primary, 7 is a medical condition that may be associated with various symptoms and si...
D-glyceric aciduria
A metabolic disorder characterized by D-glyceric acid excretion. It has been described in several patients. Cl...
DNM1L-related encephalopathy due to mitochondrial and peroxisomal fission defect
DNM1L-related encephalopathy due to mitochondrial and peroxisomal fission defect is a medical condition that m...
DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion is a medical condition that...
Developmental and epileptic encephalopathy with spike-wave activation in sleep
Developmental and epileptic encephalopathy with spike-wave activation in sleep is a medical condition that may...
Early infantile developmental and epileptic encephalopathy
Early infantile developmental and epileptic encephalopathy is a medical condition that may be associated with ...
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome is a medical...
Epilepsy of infancy with migrating focal seizures
Epilepsy of infancy with migrating focal seizures is a medical condition that may be associated with various s...
Epilepsy with auditory features
Epilepsy with auditory features is a medical condition that may be associated with various symptoms and signs....
Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation
Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation is a medica...
Familial focal epilepsy with variable foci
Familial focal epilepsy with variable foci is a medical condition that may be associated with various symptoms...
Familial infantile myoclonic epilepsy
Familial infantile myoclonic epilepsy is a medical condition that may be associated with various symptoms and ...
Gaucher disease
Gaucher disease is a medical condition that may be associated with various symptoms and signs....
Genetic epilepsy with febrile seizure plus
Genetic epilepsy with febrile seizure plus is a medical condition that may be associated with various symptoms...
Glycogen storage disease 0, muscle
Glycogen storage disease 0, muscle is a medical condition that may be associated with various symptoms and sig...
Homocystinuria due to methylene tetrahydrofolate reductase deficiency
Homocystinuria due to methylene tetrahydrofolate reductase deficiency is a medical condition that may be assoc...
Houge-Janssens syndrome 4
Houge-Janssens syndrome 4 is a medical condition that may be associated with various symptoms and signs....
Intellectual disability-seizures-abnormal gait-facial dysmorphism syndrome
Intellectual disability-seizures-abnormal gait-facial dysmorphism syndrome is a medical condition that may be ...
Japanese encephalitis
Japanese encephalitis is a medical condition that may be associated with various symptoms and signs....
Juvenile absence epilepsy
Juvenile absence epilepsy is a medical condition that may be associated with various symptoms and signs....
Kleefstra syndrome 1
An autosomal dominant non-syndromic intellectual disability that has material basis in an autosomal dominant m...
Lafora disease
Lafora disease is a medical condition that may be associated with various symptoms and signs....
Landau-Kleffner syndrome
Landau-Kleffner syndrome is a medical condition that may be associated with various symptoms and signs....
Lennox-Gastaut syndrome
Lennox-Gastaut syndrome is a medical condition that may be associated with various symptoms and signs....
Lujo hemorrhagic fever
Lujo hemorrhagic fever is a medical condition that may be associated with various symptoms and signs....
MELAS
MELAS is a medical condition that may be associated with various symptoms and signs....
MELAS syndrome
MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive mul...
Medium chain acyl-CoA dehydrogenase deficiency
Medium chain acyl-CoA dehydrogenase deficiency is a medical condition that may be associated with various symp...
Mitochondrial DNA-associated Leigh syndrome
Mitochondrial DNA-associated Leigh syndrome is a medical condition that may be associated with various symptom...
Tests providers may use to investigate bilateral tonic-clonic seizure
When investigating bilateral tonic-clonic seizure, a healthcare provider may order one or more of the following laboratory tests. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Magnesium
Measures magnesium levels, important for nerve and muscle function....
Thyroid Panel
Comprehensive thyroid testing including TSH, free T4, and free T3....
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Fasting Glucose
Measures blood sugar after fasting to screen for diabetes and prediabetes....
Hemoglobin A1c (HbA1c)
Reflects average blood sugar over the past 2-3 months....
Symptoms commonly seen alongside bilateral tonic-clonic seizure
Dysphagia
Difficulty in swallowing....
Fatigue
A subjective feeling of tiredness characterized by a lack of energy and motivation....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Muscle weakness
Reduced strength of muscles....
Seizure
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence ...
When to seek care
Seek care from a qualified healthcare provider if bilateral tonic-clonic seizure is severe, persistent, worsening, or accompanied by concerning symptoms. If you think you have a medical emergency, call your local emergency number immediately.
Frequently Asked Questions
What does the symptom bilateral tonic-clonic seizure mean?
Bilateral tonic-clonic seizure is a health sign or symptom described in medical literature. A bilateral tonic-clonic seizure is a seizure defined by a tonic (bilateral increased tone, lasting seconds to minutes) and then a clonic (bilateral sustained rhythmic jerking) phase.
Which conditions are associated with bilateral tonic-clonic seizure?
Bilateral tonic-clonic seizure has been reported in association with 120 conditions in the medical literature we index, including 3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form, Alternating hemiplegia of childhood, Angelman syndrome due to paternal uniparental disomy of chromosome 15, Bilateral generalized polymicrogyria, Bilateral polymicrogyria. These associations do not mean you have any of these conditions.
Should I see a doctor about bilateral tonic-clonic seizure?
You should discuss any persistent or concerning symptoms with a qualified healthcare provider. This website does not provide diagnosis. If you have severe symptoms or signs of a medical emergency, seek care immediately.