Salmonella Enterica Subsp. Enterica Serovar Typhi: Side Effects, Uses & Monitoring

Vivotif (Typhoid Vaccine Live Oral Ty21a) is indicated for immunization of adults and children greater than 6 years of age against disease caused by Salmonella typhi .

Data source
FDA labeling via NIH DailyMed (label 31fe1e75…)
Label version
current
Last reviewed
2026
Side effects

Reported adverse reactions

Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.

No structured frequency data available in current labeling. Consult the official label.

Uses

Labeled uses (from FDA prescribing information)

Vivotif (Typhoid Vaccine Live Oral Ty21a) is indicated for immunization of adults and children greater than 6 years of age against disease caused by Salmonella typhi . Routine typhoid vaccination is not recommended in the United States of America. Selective immunization against typhoid fever is recommended for the following groups: 1) travelers to areas in which there is a recognized risk of exposure to S. typhi , 2) persons with intimate exposure (e.g. household contact) to a S. typhi carrier, and 3) microbiology laboratorians who work frequently with S. typhi (7). There is no evidence to support the use of typhoid vaccine to control common source outbreaks, disease following natural disasters or in persons attending rural summer camps. Not all recipients of Vivotif will be fully protected against typhoid fever. Vaccinated individuals should continue to take personal precautions against exposure to typhoid organisms. The vaccine will not afford protection against species of Salmonella other than Salmonella typhi or other bacteria that cause enteric disease. The vaccine is not suitable for treatment of acute infections with S. typhi .

Related conditions

Conditions associated with Salmonella Enterica Subsp. Enterica Serovar Typhi in labeling

FAQ

Frequently Asked Questions

What is Salmonella Enterica Subsp. Enterica Serovar Typhi used for?

FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.

What are the most commonly reported side effects of Salmonella Enterica Subsp. Enterica Serovar Typhi?

Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.

Does Salmonella Enterica Subsp. Enterica Serovar Typhi require lab monitoring?

Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Salmonella Enterica Subsp. Enterica Serovar Typhi.

Where does this information come from?

All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.

Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.

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