Rizatriptan: Side Effects, Uses & Monitoring

MAXALT is indicated for the acute treatment of migraine attacks with or without aura in adults.

Data source
FDA labeling via NIH DailyMed (label 08d06e6f…)
Label version
current
Last reviewed
2026
Side effects

Reported adverse reactions

Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.

Adverse reaction (as reported in labeling)Reported frequency*
Neurological20%
Digestive13%
Pain and other pressure sensations9%
Dizziness9%
Somnolence8%
Asthenia/fatigue7%
Nausea6%
Atypical sensations5%
Paresthesia4%
Tightness/pressure and/or heaviness3%
Pain, location unspecified3%
Dry mouth3%
Pain/tightness/pressure2%
Tightness/pressure/heaviness2%
Headache2%

*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.

Uses

Labeled uses (from FDA prescribing information)

MAXALT is indicated for the acute treatment of migraine attacks with or without aura in adults. MAXALT is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine (see CONTRAINDICATIONS ). Safety and effectiveness of MAXALT have not been established for cluster headache, which is present in an older, predominantly male population.

Related conditions

Conditions associated with Rizatriptan in labeling

FAQ

Frequently Asked Questions

What is Rizatriptan used for?

FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.

What are the most commonly reported side effects of Rizatriptan?

The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Rizatriptan. Individual risk varies.

Does Rizatriptan require lab monitoring?

Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Rizatriptan.

Where does this information come from?

All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.

Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.

Educational content only: The information on Symptom Database.com is for educational purposes and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. Read our full disclaimer.