Quinapril: Side Effects, Uses & Monitoring
Quinapril hydrochloride and hydrochlorothiazide tablets are indicated for the treatment of hypertension.
- Data source
- FDA labeling via NIH DailyMed (label ba72b914…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Headache | 30% |
| Nausea and/or vomiting | 6% |
| Myalgia | 5% |
| Dizziness | 4.8% |
| Viral infection | 4% |
| Abdominal pain | 4% |
| Upper respiratory infection | 4% |
| Coughing | 3.2% |
| Fatigue | 3% |
| Rhinitis | 3% |
| Back pain | 2% |
| Insomnia | 2% |
| Dyspepsia | 2% |
| Pharyngitis | 2% |
| Vertigo | 2% |
| Chest pain | 2% |
| Diarrhea | 1.4% |
| Somnolence | 1.2% |
| Bronchitis | 1.2% |
| Asthenia | 1.1% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Quinapril hydrochloride and hydrochlorothiazide tablets are indicated for the treatment of hypertension. This fixed combination is not indicated for the initial therapy of hypertension (see DOSAGE AND ADMINISTRATION ). In using quinapril hydrochloride and hydrochlorothiazide, consideration should be given to the fact that another angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen-vascular disease. Available data are insufficient to show that quinapril does not have a similar risk (see WARNINGS: Neutropenia/Agranulocytosis ). Angioedema in Black Patients: Black patients receiving ACE inhibitor monotherapy have been reported to have a higher incidence of angioedema compared to non-blacks. It should also be noted that in controlled clinical trials, ACE inhibitors have an effect on blood pressure that is less in black patients than in non-blacks.
Conditions associated with Quinapril in labeling
Frequently Asked Questions
What is Quinapril used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Quinapril?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Quinapril. Individual risk varies.
Does Quinapril require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Quinapril.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.