Pyridostigmine: Side Effects, Uses & Monitoring

Pyridostigmine bromide is indicated for pretreatment against the lethal effects of soman nerve agent poisoning in adults.

Data source
FDA labeling via NIH DailyMed (label 0b296555…)
Label version
current
Last reviewed
2026
Side effects

Reported adverse reactions

Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.

No structured frequency data available in current labeling. Consult the official label.

Uses

Labeled uses (from FDA prescribing information)

Pyridostigmine bromide is indicated for pretreatment against the lethal effects of soman nerve agent poisoning in adults. Pyridostigmine bromide is intended for use in conjunction with protective garments, including a mask. At the first sign of nerve agent poisoning, pyridostigmine bromide should be stopped, and atropine and pralidoxime therapy started immediately. The evidence for the effectiveness of pyridostigmine bromide as pretreatment against soman-induced toxicity was derived from animal studies alone [see Clinical Studies (14) ] . FOR MILITARY MEDICAL USE ONLY

FAQ

Frequently Asked Questions

What is Pyridostigmine used for?

FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.

What are the most commonly reported side effects of Pyridostigmine?

Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.

Does Pyridostigmine require lab monitoring?

Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Pyridostigmine.

Where does this information come from?

All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.

Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.

Educational content only: The information on Symptom Database.com is for educational purposes and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. Read our full disclaimer.