Perindopril: Side Effects, Uses & Monitoring
Stable Coronary Artery Disease Perindopril erbumine tablets are indicated in patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction.
- Data source
- FDA labeling via NIH DailyMed (label fbb31482…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Cough | 12% |
| Back pain | 5.8% |
| Sinusitis | 5.2% |
| Viral infection | 3.4% |
| Upper extremity pain | 2.8% |
| Hypertonia | 2.7% |
| Dyspepsia | 1.9% |
| Fever | 1.5% |
| Proteinuria | 1.5% |
| Ear infection | 1.3% |
| Palpitation | 1.1% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Stable Coronary Artery Disease Perindopril erbumine tablets are indicated in patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction. Perindopril erbumine tablets can be used with conventional treatment for management of coronary artery disease, such as antiplatelet, antihypertensive or lipid-lowering therapy. Hypertension Perindopril erbumine tablets are indicated for the treatment of patients with essential hypertension. Perindopril erbumine tablets may be used alone or given with other classes of antihypertensives, especially thiazide diuretics. When using perindopril erbumine tablets, consideration should be given to the fact that another angiotensin converting enzyme inhibitor (captopril) has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease. Available data are insufficient to determine whether perindopril erbumine tablets has a similar potential. (See WARNINGS .) In considering use of perindopril erbumine tablets, it should be noted that in controlled trials ACE inhibitors have an effect on blood pressure that is less in black patients than in nonblacks. In…
Conditions associated with Perindopril in labeling
Coronary Artery Disease
Narrowing of the coronary arteries by plaque, reducing blood flow to the heart muscle and causing chest pain, ...
Hypertension
Chronically elevated blood pressure that puts strain on the heart, blood vessels, kidneys, and brain. Often ha...
Myocardial Infarction
A heart attack, occurring when blood flow to part of the heart muscle is blocked, causing chest pain and heart...
Frequently Asked Questions
What is Perindopril used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Perindopril?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Perindopril. Individual risk varies.
Does Perindopril require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Perindopril.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.