Pentamidine: Side Effects, Uses & Monitoring
Pentamidine isethionate for injection is indicated for the treatment of pneumonia due to Pneumocystis carinii .
- Data source
- FDA labeling via NIH DailyMed (label 860c799c…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Impaired renal function | 28.8% |
| Elevated serum creatinine | 23.6% |
| Leukopenia | 10.4% |
| Elevated liver function tests | 8.7% |
| Azotemia | 8.5% |
| Elevated blood urea nitrogen | 6.6% |
| Anorexia/nausea | 5.9% |
| Hypoglycemia | 5.9% |
| Hypotension | 5% |
| Rash | 3.3% |
| Thrombocytopenia | 2.6% |
| Confusion/hallucinations | 1.7% |
| Bad taste | 1.7% |
| Anemia | 1.2% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Pentamidine isethionate for injection is indicated for the treatment of pneumonia due to Pneumocystis carinii .
Conditions associated with Pentamidine in labeling
Frequently Asked Questions
What is Pentamidine used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Pentamidine?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Pentamidine. Individual risk varies.
Does Pentamidine require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Pentamidine.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.