Papaverine: Side Effects, Uses & Monitoring
Papaverine is recommended in various conditions accompanied by spasm of smooth muscle, such as vascular spasm associated with acute myocardial infarction (coronary occlusion), angina pectoris, peripheral and pulmonary em
- Data source
- FDA labeling via NIH DailyMed (label 5ba6e650…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
Papaverine is recommended in various conditions accompanied by spasm of smooth muscle, such as vascular spasm associated with acute myocardial infarction (coronary occlusion), angina pectoris, peripheral and pulmonary embolism, peripheral vascular disease in which there is a vasospastic element, or certain cerebral angiospastic states; and visceral spasm, as in ureteral, biliary, or gastrointestinal colic.
Conditions associated with Papaverine in labeling
Chest Pain
Discomfort or pain in the chest that can range from minor muscle strain to a life-threatening heart condition....
Myocardial Infarction
A heart attack, occurring when blood flow to part of the heart muscle is blocked, causing chest pain and heart...
Peripheral Artery Disease
Narrowing of the arteries in the limbs, usually the legs, causing cramping with walking and poor wound healing...
Pulmonary Embolism
A blockage in a lung artery, usually from a blood clot that travels from the legs, causing sudden chest pain a...
Frequently Asked Questions
What is Papaverine used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Papaverine?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Papaverine require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Papaverine.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.