Nizatidine: Side Effects, Uses & Monitoring
Nizatidine is indicated for up to 8 weeks for the treatment of active duodenal ulcer.
- Data source
- FDA labeling via NIH DailyMed (label 367a1004…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Headache | 16.6% |
| Abdominal pain | 12.5% |
| Rhinitis | 9.8% |
| Nausea | 7.4% |
| Diarrhea | 7.2% |
| Vomiting | 5.6% |
| Flatulence | 5.4% |
| Dizziness | 4.6% |
| Dyspepsia | 4.4% |
| Pain | 4.2% |
| Constipation | 3.8% |
| Insomnia | 3.4% |
| Pharyngitis | 3.3% |
| Asthenia | 3.1% |
| Back pain | 2.6% |
| Sinusitis | 2.4% |
| Chest pain | 2.3% |
| Fever | 2.3% |
| Rash | 2.1% |
| Cough, increased | 2% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Nizatidine is indicated for up to 8 weeks for the treatment of active duodenal ulcer. In most patients, the ulcer will heal within 4 weeks. Nizatidine is indicated for maintenance therapy for duodenal ulcer patients, at a reduced dosage of 150 mg h.s. after healing of an active duodenal ulcer. The consequences of continuous therapy with nizatidine for longer than 1 year are not known. Nizatidine is indicated for up to 12 weeks for the treatment of endoscopically diagnosed esophagitis, including erosive and ulcerative esophagitis, and associated heartburn due to GERD. Nizatidine is indicated for up to 8 weeks for the treatment of active benign gastric ulcer. Before initiating therapy, care should be taken to exclude the possibility of malignant gastric ulceration.
Conditions associated with Nizatidine in labeling
Frequently Asked Questions
What is Nizatidine used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Nizatidine?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Nizatidine. Individual risk varies.
Does Nizatidine require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Nizatidine.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.