Nicardipine: Side Effects, Uses & Monitoring
I.
- Data source
- FDA labeling via NIH DailyMed (label edda985c…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Pedal edema | 7.1% |
| Dizziness | 6.9% |
| Headache | 6.4% |
| Asthenia | 5.8% |
| Flushing | 5.6% |
| Increased angina | 5.6% |
| Palpitations | 3.3% |
| Nausea | 1.9% |
| Dyspepsia | 1.5% |
| Dry mouth | 1.4% |
| Somnolence | 1.4% |
| Rash | 1.2% |
| Tachycardia | 1.2% |
| Myalgia | 1% |
| Other edema | 1% |
| Paresthesia | 1% |
| Sustained tachycardia | 0.8% |
| Syncope | 0.8% |
| Constipation | 0.6% |
| Dyspnea | 0.6% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
I. Stable Angina Nicardipine hydrochloride capsules are indicated for the management of patients with chronic stable angina (effort-associated angina). Nicardipine hydrochloride capsules may be used alone or in combination with beta-blockers. II. Hypertension Nicardipine hydrochloride capsules are indicated for the treatment of hypertension. Nicardipine hydrochloride capsules may be used alone or in combination with other antihypertensive drugs. In administering nicardipine hydrochloride it is important to be aware of the relatively large peak to trough differences in blood pressure effect (See DOSAGE AND ADMINISTRATION ).
Conditions associated with Nicardipine in labeling
Frequently Asked Questions
What is Nicardipine used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Nicardipine?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Nicardipine. Individual risk varies.
Does Nicardipine require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Nicardipine.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.