Metoprolol: Side Effects, Uses & Monitoring
1.1 Hypertension Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure.
- Data source
- FDA labeling via NIH DailyMed (label 209eccb0…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Dizziness/vertigo | 1.8% |
| Bradycardia | 1.5% |
| Accident and/or injury | 1.4% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
1.1 Hypertension Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including metoprolol. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can b…
Conditions associated with Metoprolol in labeling
Chest Pain
Discomfort or pain in the chest that can range from minor muscle strain to a life-threatening heart condition....
Heart Failure
A condition in which the heart cannot pump blood effectively, leading to fluid buildup in the lungs and body a...
Hyperlipidemia
Elevated levels of cholesterol or triglycerides in the blood, a major risk factor for heart attack and stroke....
Hypertension
Chronically elevated blood pressure that puts strain on the heart, blood vessels, kidneys, and brain. Often ha...
Myocardial Infarction
A heart attack, occurring when blood flow to part of the heart muscle is blocked, causing chest pain and heart...
Stroke
Sudden interruption of blood flow to the brain, causing rapid loss of brain function. Time-critical medical em...
Frequently Asked Questions
What is Metoprolol used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Metoprolol?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Metoprolol. Individual risk varies.
Does Metoprolol require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Metoprolol.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.