Loteprednol Etabonate: Side Effects, Uses & Monitoring
LOTEMAX is indicated for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superf
- Data source
- FDA labeling via NIH DailyMed (label e7ae762f…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
LOTEMAX is indicated for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation. LOTEMAX is less effective than prednisolone acetate 1% in two 28-day controlled clinical studies in acute anterior uveitis, where 72% of patients treated with LOTEMAX experienced resolution of anterior chamber cells, compared to 87% of patients treated with prednisolone acetate 1%. The incidence of patients with clinically significant increases in IOP (≥10 mmHg) was 1% with LOTEMAX and 6% with prednisolone acetate 1%. LOTEMAX should not be used in patients who require a more potent corticosteroid for this indication. LOTEMAX is also indicated for the treatment of post-operative inflammation following ocular surgery.
Conditions associated with Loteprednol Etabonate in labeling
Conjunctivitis
Inflammation of the conjunctiva (pink eye) caused by infection or allergy, causing redness, itching, and disch...
Herpes Zoster
A painful rash (shingles) caused by reactivation of the varicella-zoster virus, often with burning pain before...
Rosacea
A chronic skin condition causing facial redness, flushing, and sometimes pimples or eye irritation....
Shingles
A painful rash caused by reactivation of the varicella-zoster virus, usually appearing as a band of blisters o...
Uveitis
Inflammation of the middle layer of the eye (uvea), causing eye pain, redness, and light sensitivity....
Frequently Asked Questions
What is Loteprednol Etabonate used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Loteprednol Etabonate?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Loteprednol Etabonate require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Loteprednol Etabonate.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.