Linaclotide: Side Effects, Uses & Monitoring
LINZESS is indicated for the treatment of: • irritable bowel syndrome with constipation (IBS-C) in adults and pediatric patients 7 years of age and older • chronic idiopathic constipation (CIC) in adults • functional con
- Data source
- FDA labeling via NIH DailyMed (label 09beda19…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
LINZESS is indicated for the treatment of: • irritable bowel syndrome with constipation (IBS-C) in adults and pediatric patients 7 years of age and older • chronic idiopathic constipation (CIC) in adults • functional constipation (FC) in pediatric patients 2 years of age and older
Conditions associated with Linaclotide in labeling
Constipation
Infrequent or difficult bowel movements, often caused by diet, dehydration, medications, or underlying conditi...
Irritable Bowel Syndrome
A common functional disorder of the gut causing abdominal pain, bloating, and changes in bowel habits such as ...
Irritable Bowel Syndrome - Constipation Predominant
A subtype of IBS characterized by constipation with abdominal pain and bloating....
Frequently Asked Questions
What is Linaclotide used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Linaclotide?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Linaclotide require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Linaclotide.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.