Lidocaine: Side Effects, Uses & Monitoring
By intravenous or intramuscular injection when oral therapy is not feasible: 1.
- Data source
- FDA labeling via NIH DailyMed (label fd895819…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
By intravenous or intramuscular injection when oral therapy is not feasible: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance). Acute adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; mineralocorticoid supplementation may be necessary, particularly when synthetic analogs are used). Preoperatively, and in the event of serious trauma or illness, in patients with known adrenal insufficiency or when adrenocortical reserve is doubtful. Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected. Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Post-traumatic osteoarthritis Synovitis of osteoarthritis Rheumatoid arthritis, including juvenile …
Conditions associated with Lidocaine in labeling
Adrenal Insufficiency
A condition in which the adrenal glands do not produce enough cortisol, causing fatigue, low blood pressure, a...
Ankylosing Spondylitis
A chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing back pain and stif...
Bursitis
Inflammation of the fluid-filled sacs (bursae) that cushion joints, causing pain and swelling, often in the sh...
Gout
A form of arthritis caused by uric acid crystal deposition, causing sudden severe joint pain, often in the big...
Osteoarthritis
The most common form of arthritis, caused by wear and tear of joint cartilage, leading to pain, stiffness, and...
Rheumatoid Arthritis
A chronic autoimmune disease causing inflammation of joints, leading to pain, swelling, stiffness, and joint d...
Frequently Asked Questions
What is Lidocaine used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Lidocaine?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Lidocaine require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Lidocaine.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.