Levonorgestrel: Side Effects, Uses & Monitoring
Levonorgestrel tablets are a prescription-only emergency contraceptive, for women age 17 and younger, that can be used to prevent pregnancy following unprotected intercourse or a known or suspected contraceptive failure.
- Data source
- FDA labeling via NIH DailyMed (label eb0e7e5e…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Nausea | 23.1% |
| Abdominal pain | 17.6% |
| Fatigue | 16.9% |
| Headache | 16.8% |
| Heavier menstrual bleeding | 13.8% |
| Lighter menstrual bleeding | 12.5% |
| Dizziness | 11.2% |
| Breast tenderness | 10.7% |
| Other complaints | 9.7% |
| Vomiting | 5.6% |
| Diarrhea | 5% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Levonorgestrel tablets are a prescription-only emergency contraceptive, for women age 17 and younger, that can be used to prevent pregnancy following unprotected intercourse or a known or suspected contraceptive failure. This product is not approved for nonprescription use. To obtain optimal efficacy, the first tablet should be taken as soon as possible within 72 hours of intercourse. The second tablet must be taken 12 hours later.
Frequently Asked Questions
What is Levonorgestrel used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Levonorgestrel?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Levonorgestrel. Individual risk varies.
Does Levonorgestrel require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Levonorgestrel.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.