Isosorbide: Side Effects, Uses & Monitoring

Isosorbide Mononitrate Extended-Release Tablets are indicated for the prevention of angina pectoris due to coronary artery disease.

Data source
FDA labeling via NIH DailyMed (label 8c104eaa…)
Label version
current
Last reviewed
2026
Side effects

Reported adverse reactions

Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.

Adverse reaction (as reported in labeling)Reported frequency*
Patients102%

*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.

Uses

Labeled uses (from FDA prescribing information)

Isosorbide Mononitrate Extended-Release Tablets are indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

Related conditions

Conditions associated with Isosorbide in labeling

FAQ

Frequently Asked Questions

What is Isosorbide used for?

FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.

What are the most commonly reported side effects of Isosorbide?

The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Isosorbide. Individual risk varies.

Does Isosorbide require lab monitoring?

Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Isosorbide.

Where does this information come from?

All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.

Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.

Educational content only: The information on Symptom Database.com is for educational purposes and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. Read our full disclaimer.