Insulin Lispro: Side Effects, Uses & Monitoring
Humalog Mix75/25, a mixture of 75% insulin lispro protamine suspension and 25% insulin lispro injection, (rDNA origin), is indicated in the treatment of patients with diabetes mellitus for the control of hyperglycemia.
- Data source
- FDA labeling via NIH DailyMed (label fbc1ff07…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
Humalog Mix75/25, a mixture of 75% insulin lispro protamine suspension and 25% insulin lispro injection, (rDNA origin), is indicated in the treatment of patients with diabetes mellitus for the control of hyperglycemia. Humalog Mix75/25 has a more rapid onset of glucose–lowering activity compared with Humulin 70/30 while having a similar duration of action. This profile is achieved by combining the rapid onset of Humalog with the intermediate action of insulin lispro protamine suspension.
Tests providers may use to monitor Insulin Lispro therapy
Fasting Glucose
Measures blood sugar after fasting to screen for diabetes and prediabetes....
Glucose Blood Test
The glucose test is a blood test used to measure glucose (blood sugar) levels. Glucose is the major source of ...
Hemoglobin A1c (HbA1c)
Reflects average blood sugar over the past 2-3 months....
Frequently Asked Questions
What is Insulin Lispro used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Insulin Lispro?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Insulin Lispro require lab monitoring?
Labeling and standard practice associate Insulin Lispro with periodic laboratory monitoring; the tests above are commonly ordered by clinicians to monitor patients on therapy. Your provider decides what is appropriate.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.