Human Vaccinia Virus Immune Globulin: Side Effects, Uses & Monitoring
VIGIV (vaccinia immune globulin intravenous, human) is indicated for the treatment and/or modification of the following conditions: • Eczema vaccinatum • Progressive vaccinia • Severe generalized vaccinia • Vaccinia infe
- Data source
- FDA labeling via NIH DailyMed (label a4f9f620…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
No structured frequency data available in current labeling. Consult the official label.
Labeled uses (from FDA prescribing information)
VIGIV (vaccinia immune globulin intravenous, human) is indicated for the treatment and/or modification of the following conditions: • Eczema vaccinatum • Progressive vaccinia • Severe generalized vaccinia • Vaccinia infections in individuals who have skin conditions such as burns, impetigo, varicella-zoster, or poison ivy; or in individuals who have eczematous skin lesions because of either the activity or extensiveness of such lesions • Aberrant infections induced by vaccinia virus that include its accidental implantation in eyes (except in cases of isolated keratitis), mouth, or other areas where vaccinia infection would constitute a special hazard. VIGIV is not considered to be effective in the treatment of postvaccinial encephalitis.
Conditions associated with Human Vaccinia Virus Immune Globulin in labeling
Atopic Dermatitis
A chronic inflammatory skin condition (eczema) causing itchy, red, dry, and cracked skin....
Chickenpox
A highly contagious viral infection causing an itchy, blister-like rash, most common in children....
Shingles
A painful rash caused by reactivation of the varicella-zoster virus, usually appearing as a band of blisters o...
Frequently Asked Questions
What is Human Vaccinia Virus Immune Globulin used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Human Vaccinia Virus Immune Globulin?
Current labeling for this ingredient does not include a structured frequency table that we can reproduce. Review the official label linked below.
Does Human Vaccinia Virus Immune Globulin require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Human Vaccinia Virus Immune Globulin.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.