Estrogens, Conjugated Synthetic A: Side Effects, Uses & Monitoring
Cenestin therapy is indicated for the: 1.
- Data source
- FDA labeling via NIH DailyMed (label 1cd07b54…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Palpitations | 1% |
| Digestive | 1% |
| Weight increase | 1% |
| Arthralgia | 1% |
| Paresthesia | 1% |
| Vertigo | 1% |
| Rhinitis | 1% |
| Asthenia | 0.7731% |
| Musculoskeletal | 0.7582% |
| Pain abdominal | 0.7159% |
| Anxiety | 0.6179% |
| Headache | 0.5748% |
| Insomnia | 0.4839% |
| Nausea | 0.4374% |
| Vasodilations | 0.4324% |
| Body as a whole | 0.4275% |
| Respiratory | 0.4173% |
| Neurological | 0.4044% |
| Vaginitis | 0.3632% |
| Pharyngitis | 0.3581% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Cenestin therapy is indicated for the: 1. Treatment of moderate-to-severe vasomotor symptoms associated with the menopause. 0.45 mg Cenestin 0.625 mg Cenestin 0.9 mg Cenestin 1.25 mg Cenestin 2. Treatment of moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. 0.3 mg Cenestin
Conditions associated with Estrogens, Conjugated Synthetic A in labeling
Frequently Asked Questions
What is Estrogens, Conjugated Synthetic A used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Estrogens, Conjugated Synthetic A?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Estrogens, Conjugated Synthetic A. Individual risk varies.
Does Estrogens, Conjugated Synthetic A require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Estrogens, Conjugated Synthetic A.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.