Enalapril: Side Effects, Uses & Monitoring
HypertensionEnalapril maleate is indicated for the treatment of hypertension.
- Data source
- FDA labeling via NIH DailyMed (label 27c971a9…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Pneumonia | 2.4% |
| Urinary tract infection | 2.4% |
| Abdominal pain | 2.1% |
| Fatigue | 1.8% |
| 1.4 (less than 0.1) | 1.7% |
| Diarrhea | 1.2% |
| Syncope | 0.9% |
| Headache | 0.9% |
| Bronchitis | 0.9% |
| Dizziness | 0.6% |
| Cough | 0.6% |
| Dyspnea | 0.4% |
| Orthostatic effects | 0.3% |
| 1.2 (less than 0.1) | 0% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
HypertensionEnalapril maleate is indicated for the treatment of hypertension. Enalapril maleate is effective alone or in combination with other antihypertensive agents, especially thiazide-type diuretics. The blood pressure lowering effects of enalapril maleate and thiazides are approximately additive. Heart FailureEnalapril maleate is indicated for the treatment of symptomatic congestive heart failure, usually in combination with diuretics and digitalis. In these patients enalapril maleate improves symptoms, increases survival, and decreases the frequency of hospitalization (see CLINICAL PHARMACOLOGY, Heart Failure, Mortality Trials for details and limitations of survival trials). Asymptomatic Left Ventricular DysfunctionIn clinically stable asymptomatic patients with left ventricular dysfunction (ejection fraction ≤35 percent), enalapril maleate decreases the rate of development of overt heart failure and decreases the incidence of hospitalization for heart failure. (See CLINICAL PHARMACOLOGY, Heart Failure, Mortality Trials for details and limitations of survival trials.) In using enalapril maleate, consideration should be given to the fact that another angiotensin converting en…
Conditions associated with Enalapril in labeling
Frequently Asked Questions
What is Enalapril used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Enalapril?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Enalapril. Individual risk varies.
Does Enalapril require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Enalapril.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.