Dipyridamole: Side Effects, Uses & Monitoring
Dipyridamole Injection is indicated as an alternative to exercise in thallium myocardial perfusion imaging for the evaluation of coronary artery disease in patients who cannot exercise adequately.
- Data source
- FDA labeling via NIH DailyMed (label 6093dcd9…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Chest pain/angina pectoris | 19.7% |
| Headache | 12.2% |
| Dizziness | 11.8% |
| Hypotension | 4.6% |
| Nausea | 4.6% |
| Flushing | 3.4% |
| Dyspnea | 2.6% |
| Pain unspecified | 2.6% |
| Blood pressure lability | 1.6% |
| Hypertension | 1.5% |
| Paresthesia | 1.3% |
| Fatigue | 1.2% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Dipyridamole Injection is indicated as an alternative to exercise in thallium myocardial perfusion imaging for the evaluation of coronary artery disease in patients who cannot exercise adequately. In a study of about 1100 patients who underwent coronary arteriography and Dipyridamole Injection assisted thallium imaging, the results of both tests were interpreted blindly and the sensitivity and specificity of the dipyridamole thallium study in predicting the angiographic outcome were calculated. The sensitivity of the dipyridamole test (true positive dipyridamole divided by the total number of patients with positive angiography) was about 85%. The specificity (true negative divided by the number of patients with negative angiograms) was about 50%. In a subset of patients who had exercise thallium imaging as well as dipyridamole thallium imaging, sensitivity and specificity of the two tests were almost identical.
Conditions associated with Dipyridamole in labeling
Frequently Asked Questions
What is Dipyridamole used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Dipyridamole?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Dipyridamole. Individual risk varies.
Does Dipyridamole require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Dipyridamole.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.