Celecoxib: Side Effects, Uses & Monitoring
Carefully consider the potential benefits and risks of celecoxib and other treatment options before deciding to use celecoxib.
- Data source
- FDA labeling via NIH DailyMed (label 1aae31e7…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Any event | 72% |
| Gastrointestinal | 36% |
| Infections | 27% |
| Nervous system | 21% |
| Headache | 20.2% |
| General | 18% |
| Skin & subcutaneous | 18% |
| Musculoskeletal | 17% |
| Headache nos | 16% |
| Respiratory | 15% |
| Dyspepsia | 12.8% |
| Hypertension | 12.5% |
| Vomiting nos | 11% |
| Pyrexia | 11% |
| Investigations* | 11% |
| Abdominal pain upper | 10% |
| Upper respiratory infection | 9.9% |
| Diarrhea | 9.3% |
| Abdominal pain | 9% |
| Diarrhea nos | 8% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
Carefully consider the potential benefits and risks of celecoxib and other treatment options before deciding to use celecoxib. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals [see Warnings and Precautions (5) ] 1.1 Osteoarthritis (OA)Celecoxib is indicated for relief of the signs and symptoms of OA [see Clinical Studies (14.1) ] 1.2 Rheumatoid Arthritis (RA)Celecoxib is indicated for relief of the signs and symptoms of RA [see Clinical Studies (14.2) ] 1.3 Juvenile Rheumatoid Arthritis (JRA)Celecoxib is indicated for relief of the signs and symptoms of JRA in patients 2 years and older [see Clinical Studies (14.3) ] 1.4 Ankylosing Spondylitis (AS)Celecoxib is indicated for the relief of signs and symptoms of AS [see Clinical Studies (14.4) ] 1.5 Acute Pain (AP)Celecoxib is indicated for the management of AP in adults [see Clinical Studies (14.5) ] 1.6 Primary Dysmenorrhea (PD)Celecoxib is indicated for the treatment of PD [see Clinical Studies (14.5) ]
Conditions associated with Celecoxib in labeling
Ankylosing Spondylitis
A chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing back pain and stif...
Osteoarthritis
The most common form of arthritis, caused by wear and tear of joint cartilage, leading to pain, stiffness, and...
Rheumatoid Arthritis
A chronic autoimmune disease causing inflammation of joints, leading to pain, swelling, stiffness, and joint d...
Frequently Asked Questions
What is Celecoxib used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Celecoxib?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Celecoxib. Individual risk varies.
Does Celecoxib require lab monitoring?
Monitoring needs vary. Ask your healthcare provider whether any lab tests apply while taking Celecoxib.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.