Atorvastatin: Side Effects, Uses & Monitoring
CADUET (amlodipine and atorvastatin) is indicated in patients for whom treatment with both amlodipine and atorvastatin is appropriate.
- Data source
- FDA labeling via NIH DailyMed (label 909fad96…)
- Label version
- current
- Last reviewed
- 2026
Reported adverse reactions
Reactions listed in current FDA labeling, with the highest frequency reported across summarized placebo-controlled trials.
| Adverse reaction (as reported in labeling) | Reported frequency* |
|---|---|
| Edema | 10.8% |
| Headache | 7.8% |
| Palpitations | 4.5% |
| Fatigue | 4.5% |
| Dizziness | 3.4% |
| Nausea | 2.9% |
| Flushing | 2.6% |
| Abdominal pain | 1.6% |
| Somnolence | 1.4% |
*Highest percentage reported for the active moiety across placebo-controlled trial tables in current FDA labeling. Values reflect trial reporting, not your individual risk.
Labeled uses (from FDA prescribing information)
CADUET (amlodipine and atorvastatin) is indicated in patients for whom treatment with both amlodipine and atorvastatin is appropriate. Amlodipine1. Hypertension : Amlodipine is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents; 2. Coronary Artery Disease (CAD) Chronic Stable Angina: Amlodipine is indicated for the treatment of chronic stable angina. Amlodipine may be used alone or in combination with other antianginal or antihypertensive agents; Vasospastic Angina (Prinzmetal's or Variant Angina): Amlodipine is indicated for the treatment of confirmed or suspected vasospastic angina. Amlodipine may be used as monotherapy or in combination with other antianginal drugs. Angiographically Documented CAD: In patients with recently documented CAD by angiography and without heart failure or an ejection fraction less than 40%, amlodipine is indicated to reduce the risk of hospitalization due to angina and to reduce the risk of a coronary revascularization procedure. AND AtorvastatinTherapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased…
Tests providers may use to monitor Atorvastatin therapy
Conditions associated with Atorvastatin in labeling
Chest Pain
Discomfort or pain in the chest that can range from minor muscle strain to a life-threatening heart condition....
Coronary Artery Disease
Narrowing of the coronary arteries by plaque, reducing blood flow to the heart muscle and causing chest pain, ...
Heart Failure
A condition in which the heart cannot pump blood effectively, leading to fluid buildup in the lungs and body a...
Hypertension
Chronically elevated blood pressure that puts strain on the heart, blood vessels, kidneys, and brain. Often ha...
Myocardial Infarction
A heart attack, occurring when blood flow to part of the heart muscle is blocked, causing chest pain and heart...
Stroke
Sudden interruption of blood flow to the brain, causing rapid loss of brain function. Time-critical medical em...
Frequently Asked Questions
What is Atorvastatin used for?
FDA labeling lists the approved uses shown above under "Labeled uses." This summary is informational; only a qualified prescriber can determine whether a medication is appropriate for you.
What are the most commonly reported side effects of Atorvastatin?
The table above shows adverse reactions and the highest frequencies reported in placebo-controlled trials summarized in current FDA labeling for Atorvastatin. Individual risk varies.
Does Atorvastatin require lab monitoring?
Labeling and standard practice associate Atorvastatin with periodic laboratory monitoring; the tests above are commonly ordered by clinicians to monitor patients on therapy. Your provider decides what is appropriate.
Where does this information come from?
All clinical facts on this page were extracted from the current FDA-registered product labeling for this ingredient, published by manufacturers through NIH DailyMed. See the source link below.
Medical disclaimer: Educational content extracted from public FDA labeling. Not medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.