deficiency of adenosine deaminase 2
A rare autoinflammatory disease characterized by a broad clinical phenotype of systemic inflammation, vasculitis, early-onset stroke, immunodeficiency and bone marrow failure. The disease typically presents in young children, although adult cases are being discovered.
Also known as: ADA2 deficiency, DADA2, adenosine deaminase 2 deficiency, childhood-onset polyarteritis nodosa, deficiency of adenosine deaminase 2, polyarteritis nodosa, childhood-onset, vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome, PAN.
Category: General
Symptoms associated with deficiency of adenosine deaminase 2
The following symptoms have been associated with deficiency of adenosine deaminase 2 in medical literature. Not everyone experiences the same symptoms.
Abdominal pain
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perc...
Arthralgia
Joint pain....
Fever
Body temperature elevated above the normal range....
Headache
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve....
Hypertension
The presence of chronic increased pressure in the systemic arterial system....
Myalgia
Pain in muscle....
Recurrent fever
Periodic (episodic or recurrent) bouts of fever....
Skin rash
A red eruption of the skin....
Tests used to investigate deficiency of adenosine deaminase 2
Healthcare providers may order these tests when evaluating deficiency of adenosine deaminase 2. Test selection is a clinical decision made by a qualified professional.
CBC with Differential
Measures red blood cells, white blood cells, and platelets to help evaluate overall health and detect disorder...
Comprehensive Metabolic Panel (CMP)
Measures 14 substances in the blood to assess kidney and liver function, electrolyte balance, and blood sugar ...
Urinalysis
Examines urine content to help detect urinary tract infections, kidney disease, and diabetes....
Conditions with overlapping symptoms
These conditions share symptoms with deficiency of adenosine deaminase 2, which is why a clinical evaluation is important.
Behçet disease
Behçet disease is a medical condition that may be associated with various symptoms and signs....
Crimean-Congo hemorrhagic fever
Crimean-Congo hemorrhagic fever is a medical condition that may be associated with various symptoms and signs....
Eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis is a medical condition that may be associated with various sympt...
Granulomatosis with polyangiitis
Granulomatosis with polyangiitis is a medical condition that may be associated with various symptoms and signs...
Marburg hemorrhagic fever
Marburg hemorrhagic fever is a medical condition that may be associated with various symptoms and signs....
Yellow fever
Yellow fever is a medical condition that may be associated with various symptoms and signs....
Frequently Asked Questions
What is deficiency of adenosine deaminase 2?
deficiency of adenosine deaminase 2 is a health condition described in medical literature. A rare autoinflammatory disease characterized by a broad clinical phenotype of systemic inflammation, vasculitis, early-onset stroke, immunodeficiency and bone marrow failure. The disease typically presents in young children, although adult cases are being discovered.
What are the symptoms of deficiency of adenosine deaminase 2?
deficiency of adenosine deaminase 2 is associated with 8 symptoms in the medical literature we index, including Abdominal pain, Arthralgia, Fever, Headache, Hypertension, Myalgia. Symptoms vary widely between individuals.
How is deficiency of adenosine deaminase 2 diagnosed or investigated?
A healthcare provider may use a combination of medical history, physical examination, and tests. Common tests associated with deficiency of adenosine deaminase 2 include CBC with Differential, Comprehensive Metabolic Panel (CMP), Urinalysis. This information is educational, not a diagnosis.
Is SymptomDatabase.com diagnosing me?
No. SymptomDatabase.com does not provide diagnosis. If you are concerned you may have deficiency of adenosine deaminase 2, please discuss your symptoms with a qualified healthcare provider.